Non-invasive assessment of liver fibrosis and prognosis: an update on serum and elastography markers

U Agbim, SK Asrani - Expert review of gastroenterology & …, 2019 - Taylor & Francis
Introduction: Non-invasive assessment of fibrosis is increasingly utilized in clinical practice
to diagnose hepatic fibrosis. Non-invasive assessment of liver fibrosis relies on biologic …

Mac-2 binding protein glycan isomer (M2BPGi) is a new serum biomarker for assessing liver fibrosis: more than a biomarker of liver fibrosis

K Shirabe, Y Bekki, D Gantumur, K Araki, N Ishii… - Journal of …, 2018 - Springer
Assessing liver fibrosis is important for predicting the efficacy of antiviral therapy and patient
prognosis. Liver biopsy is the gold standard for diagnosing liver fibrosis, despite its …

EASL Clinical Practice Guidelines: The diagnosis and management of patients with primary biliary cholangitis

GM Hirschfield, U Beuers, C Corpechot, P Invernizzi… - Journal of …, 2017 - Elsevier
Primary biliary cholangitis (PBC) is a chronic inflammatory autoimmune cholestatic liver
disease, which when untreated will culminate in end-stage biliary cirrhosis. Diagnosis is …

[HTML][HTML] Non-invasive markers of liver fibrosis: adjuncts or alternatives to liver biopsy?

JL Chin, M Pavlides, A Moolla, JD Ryan - Frontiers in pharmacology, 2016 - frontiersin.org
Liver fibrosis reflects sustained liver injury often from multiple, simultaneous factors. Whilst
the presence of mild fibrosis on biopsy can be a reassuring finding, the identification of …

Hepatic stellate cells secreting WFA+‐M2BP: Its role in biological interactions with Kupffer cells

Y Bekki, T Yoshizumi, S Shimoda, S Itoh… - Journal of …, 2017 - Wiley Online Library
Abstract Background and Aim Hepatic stellate cells (HSCs) play a central role in hepatic
fibrosis and are regulated by Kupffer cells (KCs). Wisteria floribunda agglutinin‐positive Mac …

[HTML][HTML] Mild drinking habit is a risk factor for hepatocarcinogenesis in non-alcoholic fatty liver disease with advanced fibrosis

T Kimura, N Tanaka, N Fujimori, A Sugiura… - World journal of …, 2018 - ncbi.nlm.nih.gov
AIM The impact of mild drinking habit (less than 20 g/d of ethanol) on the clinical course of
non-alcoholic fatty liver disease (NAFLD) has not been determined. We examined the …

Clinical significance of serum Wisteria floribunda agglutinin positive Mac‐2‐binding protein level and high‐sensitivity C‐reactive protein concentration in autoimmune …

H Nishikawa, H Enomoto, Y Iwata… - Hepatology …, 2016 - Wiley Online Library
Aim We aimed to examine the relationship between the Wisteria floribunda agglutinin
positive Mac‐2‐binding protein (WFA+‐M2BP) level and high‐sensitivity C‐reactive protein …

Serum WFA+‐M2BP levels for evaluation of early stages of liver fibrosis in patients with chronic hepatitis B virus infection

X Zou, MY Zhu, DM Yu, W Li, DH Zhang… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Accurate evaluation of liver fibrosis is crucial for predicting
progression of chronic hepatitis B virus (HBV) infection. We assessed the utility of a novel …

[HTML][HTML] Clinical utility of Mac-2 binding protein glycosylation isomer in chronic liver diseases

N Tamaki, M Kurosaki, R Loomba… - Annals of laboratory …, 2021 - ncbi.nlm.nih.gov
An accurate evaluation of liver fibrosis is clinically important in chronic liver diseases. Mac-2
binding protein glycosylation isomer (M2BPGi) is a novel serum marker for liver fibrosis. In …

[HTML][HTML] Association of serum autotaxin levels with liver fibrosis in patients with chronic hepatitis C

T Yamazaki, S Joshita, T Umemura, Y Usami… - Scientific reports, 2017 - nature.com
Metabolized by liver sinusoidal endothelial cells, autotaxin (ATX) is a secreted enzyme
considered to be associated with liver damage. We sought to clarify the diagnostic ability of …