Etiopathogenesis of osteoarthritis

KD Brandt, P Dieppe, EL Radin - Rheumatic Disease Clinics of North …, 2008 - Elsevier
In this article, the authors posit that, because osteoarthritis (OA) involves all of the tissues of
the synovial joint, the emphasis on the loss of cartilage, in particular, is misguided. In …

ADAMTS‐4 and ADAMTS‐5: key enzymes in osteoarthritis

P Verma, K Dalal - Journal of cellular biochemistry, 2011 - Wiley Online Library
Osteoarthritis (OA) is a progressive disease of the joints characterized by degradation of
articular cartilage. Although disease initiation may be multi‐factorial, the cartilage …

Risk factors for the incidence and progression of radiographic knee osteoarthritis

C Cooper, S Snow, TE McAlindon… - … : Official Journal of …, 2000 - Wiley Online Library
Objective Preventive strategies against knee osteoarthritis (OA) require a knowledge of risk
factors that influence the initiation of the disorder and its subsequent progression. This …

The impact of osteoarthritis: implications for research.

JA Buckwalter, C Saltzman, T Brown - Clinical Orthopaedics and …, 2004 - journals.lww.com
Osteoarthritis, the clinical syndrome of joint pain and dysfunction caused by joint
degeneration, affects more people than any other joint disease. There are no consistently …

Study of 500 patients with limb joint osteoarthritis. I. Analysis by age, sex, and distribution of symptomatic joint sites.

J Cushnaghan, P Dieppe - Annals of the rheumatic diseases, 1991 - ard.bmj.com
Five hundred subjects with symptomatic limb joint osteoarthritis, who had been referred to a
rheumatologist, were enrolled into a continuing study. They comprised 342 women (mean …

Indices of severity and disease activity for osteoarthritis

M Lequesne - Seminars in arthritis and rheumatism, 1991 - Elsevier
Several indices have recently been constructed by rheumatologists for the assessment of
clinical status in osteoarthritis of the extremities. These include the algofunctional indices for …

[图书][B] Stories from the skeleton: behavioral reconstruction in human osteology

R Jurmain - 2013 - taylorfrancis.com
This volume raises central theoretical issues regarding behavioural reconstruction in human
osteological research. Because behavioural reconstructions have become increasingly …

Prediction of the progression of joint space narrowing in osteoarthritis of the knee by bone scintigraphy.

P Dieppe, J Cushnaghan, P Young… - Annals of the rheumatic …, 1993 - ard.bmj.com
OBJECTIVES--To test the hypothesis that bone scintigraphy will predict the outcome of
osteoarthritis (OA) of the knee joint. METHODS--Ninety four patients (65 women, 29 men; …

Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity.

TD Spector, DJ Hart, DV Doyle - Annals of the rheumatic diseases, 1994 - ard.bmj.com
OBJECTIVES--The natural history of knee osteoarthritis (OA) is poorly understood. The
principal aim was to assess the rate of contralateral knee OA in middle aged women in the …

A 12 year follow up study in the general population on prognostic factors of cartilage loss in osteoarthritis of the knee.

JS Schouten, FA Van den Ouweland… - Annals of the rheumatic …, 1992 - ard.bmj.com
The natural history and prognostic factors of cartilage loss in osteoarthritis of the knee were
studied in subjects from a general population survey on rheumatic diseases in 1975-8 …