The immunological barrier to xenotransplantation

M Cascalho, JL Platt - Immunity, 2001 - cell.com
The transplantation of cells, tissue, or organs between the host. However, diversity of
antigens is not sufficient disparate species, that is,“xenotransplantation,” has to explain the …

Accommodation: preventing injury in transplantation and disease

CA Koch, ZI Khalpey, JL Platt - The Journal of Immunology, 2004 - journals.aai.org
Humoral immunity, as a cause of damage to blood vessels, poses a major barrier to
successful transplantation of organs. Under some conditions, humoral immunity causes little …

Report from a consensus conference on antibody-mediated rejection in heart transplantation

J Kobashigawa, MG Crespo-Leiro… - The Journal of Heart and …, 2011 - Elsevier
BACKGROUND: The problem of AMR remains unsolved because standardized schemes for
diagnosis and treatment remains contentious. Therefore, a consensus conference was …

Carbohydrates in xenotransplantation

M Ezzelarab, D Ayares… - Immunology and cell …, 2005 - Wiley Online Library
The success of allotransplantation has led to an increasing shortage of human organs from
deceased donors. This crisis could be resolved by the use of organs from an anatomically …

Protective effect of rutin on humoral and cell mediated immunity in rat model

A Ganeshpurkar, AK Saluja - Chemico-Biological Interactions, 2017 - Elsevier
Diet and dietary intake can persuade the development, safeguard and proper functioning of
immune system. Ruin, an important bioflavonoid, is abundantly found in various foodstuffs …

Immune response, accommodation, and tolerance to transplantation carbohydrate antigens

U Galili - Transplantation, 2004 - journals.lww.com
The carbohydrate antigens, blood groups A and B, and the α-gal epitope (Galα1–3Gal) are
major risk factors in transplantation. Transplantation across ABO barriers may result in …

A unique thymic fibroblast population revealed by the monoclonal antibody MTS-15

DHD Gray, D Tull, T Ueno, N Seach… - The Journal of …, 2007 - journals.aai.org
T cell differentiation in the thymus is dependent upon signals from thymic stromal cells. Most
studies into the nature of these signals have focused only on the support provided by the …

Xenotransplantation and ABO incompatible transplantation: the similarities they share

U Galili - Transfusion and Apheresis Science, 2006 - Elsevier
Transplantation of kidney allografts across the ABO barrier has been feasible with the
development of technologies for removal of anti-blood group antibodies from the circulation …

Accommodation in allogeneic and xenogeneic organ transplantation: Prevalence, impact, and implications for monitoring and for therapeutics

JL Platt, M Cascalho - Human immunology, 2023 - Elsevier
Accommodation refers to acquired resistance of organs or tissues to immune or
inflammatory reactions that might otherwise cause severe injury or rejection. As first …

Accommodation in organ transplantation

RJ Lynch, JL Platt - Current opinion in organ transplantation, 2008 - journals.lww.com
Accommodation may be a common, perhaps the most common, outcome of organ
transplantation and, in some systems, a predictable outcome of organ xenotransplantation …