Are we close to defining a metabolomic signature of human obesity? A systematic review of metabolomics studies
OD Rangel-Huerta, B Pastor-Villaescusa, A Gil - Metabolomics, 2019 - Springer
Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …
weight in relation to height, mainly due to the accumulation of fat, and is considered a …
Significance of l‐carnitine for human health
MM Adeva‐Andany, I Calvo‐Castro… - IUBMB …, 2017 - Wiley Online Library
Carnitine acyltransferases catalyze the reversible transfer of acyl groups from acyl‐
coenzyme A esters to l‐carnitine, forming acyl‐carnitine esters that may be transported …
coenzyme A esters to l‐carnitine, forming acyl‐carnitine esters that may be transported …
Effects of weight loss using supplementation with Lactobacillus strains on body fat and medium-chain acylcarnitines in overweight individuals
M Kim, M Kim, M Kang, HJ Yoo, MS Kim, YT Ahn… - Food & function, 2017 - pubs.rsc.org
Our previous study showed that supplementation with a combination of Lactobacillus
curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 reduced …
curvatus (L. curvatus) HY7601 and Lactobacillus plantarum (L. plantarum) KY1032 reduced …
Metabolomics identifies increases in the acylcarnitine profiles in the plasma of overweight subjects in response to mild weight loss: a randomized, controlled design …
M Kang, HJ Yoo, M Kim, M Kim, JH Lee - Lipids in health and disease, 2018 - Springer
Background Using metabolomics technique to analyze the response to a dietary intervention
generates valuable information concerning the effects of the prescribed diet on metabolic …
generates valuable information concerning the effects of the prescribed diet on metabolic …
Altered plasma amino acids and lipids associated with abnormal glucose metabolism and insulin resistance in older adults
RD Semba, M Gonzalez-Freire… - The Journal of …, 2018 - academic.oup.com
Abstract Context and Objectives Glucose metabolism becomes progressively impaired with
older age. Fasting glucose and insulin resistance are risk factors for premature death and …
older age. Fasting glucose and insulin resistance are risk factors for premature death and …
Effect of general adiposity and central body fat distribution on the circulating metabolome: A multicohort nontargeted metabolomics observational and mendelian …
S Ahmad, U Hammar, B Kennedy, S Salihovic… - Diabetes, 2022 - Am Diabetes Assoc
Obesity is associated with adverse health outcomes, but the metabolic effects have not yet
been fully elucidated. We aimed to investigate the association between adiposity and …
been fully elucidated. We aimed to investigate the association between adiposity and …
A data integration multi-omics approach to study calorie restriction-induced changes in insulin sensitivity
Background: The mechanisms responsible for calorie restriction (CR)-induced improvement
in insulin sensitivity (IS) have not been fully elucidated. Greater insight can be achieved …
in insulin sensitivity (IS) have not been fully elucidated. Greater insight can be achieved …
Decreases in circulating concentrations of long-chain acylcarnitines and free fatty acids during the glucose tolerance test represent tissue-specific insulin sensitivity
E Makarova, M Makrecka-Kuka, K Vilks… - Frontiers in …, 2019 - frontiersin.org
Background: Insulin plays a pivotal role in the regulation of both carbohydrate and lipid
intermediate turnover and metabolism. In the transition from a fasted to fed state, insulin …
intermediate turnover and metabolism. In the transition from a fasted to fed state, insulin …
Effects of gut microbiota and fatty acid metabolism on dyslipidemia following weight-loss diets in women: Results from a randomized controlled trial
Background & aims In our early feeding trial among overweight and obese Chinese women,
both low-carbohydrate (LC) and calorie-restricted (CR) diets reduced weight and fat mass …
both low-carbohydrate (LC) and calorie-restricted (CR) diets reduced weight and fat mass …
Obesity genomics and metabolomics: a nexus of cardiometabolic risk
JA Regan, SH Shah - Current cardiology reports, 2020 - Springer
Abstract Purpose of Review Obesity is a significant international public health epidemic with
major downstream consequences on morbidity and mortality. While lifestyle factors …
major downstream consequences on morbidity and mortality. While lifestyle factors …