Epigenetics regulates gene expression and has been confirmed to play a critical role in a
variety of metabolic diseases, such as diabetes, obesity, non-alcoholic fatty liver disease …

MicroRNAs (miRNAs) are short non-coding RNAs that inhibit the expression of target genes
by directly binding to their mRNAs. miRNAs are transcribed as precursor molecules, which …

MicroRNAs (miRNAs) are short endogenously expressed RNAs that have the potential to
regulate the expression of any RNA. This potential has led to the publication of several …

MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …

Summary N 6-methyladenosine (m 6 A) is the most abundant internal modification of
messenger RNA. While the presence of m 6 A on transcripts can impact nuclear RNA fates …

MicroRNAs (miRNAs) are small non-coding RNAs that function as guide molecules in RNA
silencing. Targeting most protein-coding transcripts, miRNAs are involved in nearly all …

The first step in the biogenesis of microRNAs is the processing of primary microRNAs (pri-
miRNAs) by the microprocessor complex, composed of the RNA-binding protein DGCR8 …

Atherosclerosis and its attendant clinical complications, such as myocardial infarction,
stroke, and peripheral artery disease, are the leading cause of morbidity and mortality in …

Cancer has long been viewed as a disease of normal development gone awry. Cancer stem-
like cells (CSCs), also termed as tumor-initiating cells (TICs), are increasingly recognized as …

Biogenesis of canonical microRNAs (miRNAs) involves multiple steps: nuclear processing of
primary miRNA (pri-miRNA) by DROSHA, nuclear export of precursor miRNA (pre-miRNA) …