MicroRNA let-7 and viral infections: focus on mechanisms of action

A Letafati, S Najafi, M Mottahedi, M Karimzadeh… - Cellular & Molecular …, 2022 - Springer
MicroRNAs (miRNAs) are fundamental post-transcriptional modulators of several critical
cellular processes, a number of which are involved in host defense mechanisms. In …

[HTML][HTML] Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents

M Hashemi, MSA Mirdamadi, Y Talebi… - Pharmacological …, 2023 - Elsevier
The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …

Long noncoding RNA MEG3 is downregulated in cervical cancer and affects cell proliferation and apoptosis by regulating miR-21

J Zhang, T Yao, Y Wang, J Yu, Y Liu… - Cancer biology & …, 2016 - Taylor & Francis
Recent research has found that long noncoding RNAs (lncRNAs) were involved in various
human cancers. However, the role of these lncRNAs in cervical cancer remains unexplored …

microRNAs: new prognostic, diagnostic, and therapeutic biomarkers in cervical cancer

JS Nahand, S Taghizadeh‐boroujeni… - Journal of cellular …, 2019 - Wiley Online Library
Cervical cancer is as a kind of cancer beginning from the cervix. Given that cervical cancer
could be observed in women who infected with papillomavirus, regular oral contraceptives …

[HTML][HTML] Effects of resveratrol, curcumin, berberine and other nutraceuticals on aging, cancer development, cancer stem cells and microRNAs

JA McCubrey, K Lertpiriyapong, LS Steelman… - Aging (Albany …, 2017 - ncbi.nlm.nih.gov
Natural products or nutraceuticals have been shown to elicit anti-aging, anti-cancer and
other health-enhancing effects. A key target of the effects of natural products may be the …

MicroRNA involvement in signaling pathways during viral infection

MG Barbu, CE Condrat, DC Thompson… - Frontiers in cell and …, 2020 - frontiersin.org
The study of miRNAs started in 1993, when Lee et al. observed their involvement in the
downregulation of a crucial protein known as LIN-14 in the nematode Caenorhabditis …

Breast cancer tumor microenvironment affects Treg/IL-17-producing Treg/Th17 cell axis: Molecular and therapeutic perspectives

F Seif, Z Torki, H Zalpoor, M Habibi… - Molecular Therapy …, 2023 - cell.com
The tumor microenvironment (TME) comprises a variety of immune cells, among which T
cells exert a prominent axial role in tumor development or anti-tumor responses in patients …

MiRNA-based therapeutic intervention of cancer

S Naidu, P Magee, M Garofalo - Journal of hematology & oncology, 2015 - Springer
MicroRNAs (miRNAs) are important modulators of eukaryotic gene expression. By targeting
protein coding transcripts, miRNAs influence the cellular transcriptome and proteome, thus …

Manipulation of JAK/STAT signalling by high-risk HPVs: Potential therapeutic targets for HPV-associated malignancies

EL Morgan, A Macdonald - Viruses, 2020 - mdpi.com
Human papillomaviruses (HPVs) are small, DNA viruses that cause around 5% of all
cancers in humans, including almost all cervical cancer cases and a significant proportion of …

MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt-mTOR signaling pathway

L Song, S Liu, L Zhang, H Yao, F Gao, D Xu, Q Li - Tumor Biology, 2016 - Springer
MiR-21 is an important microRNA (miRNA) modulating radiosensitivity of cervical cancer
cells. However, the underlying mechanism of miR-21 upregulation in radioresistant cervical …