Despite improvements in interventional and pharmacological therapy of atherosclerotic
disease, it is still the leading cause of death in the developed world. Hence, there is a need …

Background—Despite rapid clinical translation and widespread enthusiasm, the therapeutic
benefits of adult bone marrow cell (BMC) transplantation in patients with ischemic heart …

Cardiovascular diseases are known as one of major causes of morbidity and mortality
worldwide. Despite the many advancement in therapies are associated with cardiovascular …

Rationale: Notwithstanding the uncertainties about the outcomes of bone marrow cell (BMC)
therapy for heart repair, further insights are critically needed to improve this promising …

Humans and other mammals have three main adipose tissue depots: visceral white adipose
tissue, subcutaneous white adipose tissue and brown adipose tissue, each of which …

Rationale: CD34+ transplantation in dilated cardiomyopathy was associated with short-term
improvement in left ventricular ejection fraction and exercise tolerance. Objective: We …

After the onset of ischemia, cardiac or skeletal muscle undergoes a continuum of molecular,
cellular, and extracellular responses that determine the function and the remodeling of the …

Rationale: Hypoplastic left heart syndrome (HLHS) remains a lethal congenital cardiac
defect. Recent studies have suggested that intracoronary administration of autologous …

Background Cell transplantation offers a potential therapeutic approach to the repair and
regeneration of damaged vascular and cardiac tissue after acute myocardial infarction (AMI) …

Bone-marrow-derived EPCs (endothelial progenitor cells) play an integral role in the
regulation and protection of the endothelium, as well as new vessel formation. Peripheral …