Conspectus Rigorous substrate selectivity is a hallmark of enzyme catalysis. This selectivity
is generally ascribed to a thermodynamically favorable process of substrate binding to the …

Ni–Fe–S-dependent carbon monoxide dehydrogenases (CODHs) are enzymes that
interconvert CO and CO2 by using their catalytic Ni–Fe–S C-cluster and their Fe–S B-and D …

Approximately two-thirds of the estimated one-billion metric tons of methane produced
annually by methanogens is derived from the cleavage of acetate. Acetate is broken down …

Gas-fermenting acetogens can upgrade one-carbon (C1) compounds (such as CO2 and
CO) to the two-carbon (C2) metabolite acetyl coenzyme A (CoA) and convert sugar …

One of the seven natural CO 2 fixation pathways, the anaerobic Wood-Ljungdahl pathway
(WLP) is unique in generating CO as a metabolic intermediate, operating through …

The formation of carbon–carbon bonds from prebiotic precursors such as carbon dioxide
represents the foundation of all primordial life processes. In extant organisms, this reaction is …

Carbon dioxide is a major greenhouse gas, and its fixation and transformation are receiving
increasing attention. Biofixation of CO2 is an eco–friendly and efficient way to reduce CO2 …

The Wood–Ljungdahl Pathway is a unique biological mechanism of carbon dioxide and
carbon monoxide fixation proposed to operate through nickel-based organometallic …

Metalloenzymes have been detailed in The Enzymes since its inception over half a century
ago. Here, I review selected metal-containing enzyme highlights from early chapters in this …

My personal introduction to the environmental outcome from microbial metabolism of
minerals came when I was an undergraduate student in the laboratory of my science advisor …