Stress and cognition

C Sandi - Wiley Interdisciplinary Reviews: Cognitive Science, 2013 - Wiley Online Library
Stress can affect cognition in many ways, with the outcome (ie, facilitating or impairing)
depending on a combination of factors related to both stress and the cognitive function …

Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy

MJ Millan, Y Agid, M Brüne, ET Bullmore… - Nature reviews Drug …, 2012 - nature.com
Studies of psychiatric disorders have traditionally focused on emotional symptoms such as
depression, anxiety and hallucinations. However, poorly controlled cognitive deficits are …

An antibody-based molecular switch for continuous small-molecule biosensing

IAP Thompson, J Saunders, L Zheng, AA Hariri… - Science …, 2023 - science.org
We present a generalizable approach for designing biosensors that can continuously detect
small-molecule biomarkers in real time and without sample preparation. This is achieved by …

[HTML][HTML] Importance of the brain corticosteroid receptor balance in metaplasticity, cognitive performance and neuro-inflammation

ER De Kloet, OC Meijer, AF de Nicola… - Frontiers in …, 2018 - Elsevier
Bruce McEwen's discovery of receptors for corticosterone in the rat hippocampus introduced
higher brain circuits in the neuroendocrinology of stress. Subsequently, these receptors …

[HTML][HTML] Reducing social stress elicits emotional contagion of pain in mouse and human strangers

LJ Martin, G Hathaway, K Isbester, S Mirali, EL Acland… - Current Biology, 2015 - cell.com
Empathy for another's physical pain has been demonstrated in humans [1] and mice [2]; in
both species, empathy is stronger between familiars. Stress levels in stranger dyads are …

Spironolactone as a potential new pharmacotherapy for alcohol use disorder: convergent evidence from rodent and human studies

M Farokhnia, CT Rentsch, V Chuong, MA McGinn… - Molecular …, 2022 - nature.com
Evidence suggests that spironolactone, a nonselective mineralocorticoid receptor (MR)
antagonist, modulates alcohol seeking and consumption. Therefore, spironolactone may …

[HTML][HTML] The brain mineralocorticoid receptor and stress resilience

F ter Heegde, RH De Rijk, CH Vinkers - Psychoneuroendocrinology, 2015 - Elsevier
Stress exposure activates the HPA-axis and results in the release of corticosteroids which
bind to two receptor types in the brain: the mineralocorticoid receptor (MR) and the …

Top‐down and bottom‐up control of stress‐coping

ER de Kloet, SF de Kloet, CS de Kloet… - Journal of …, 2019 - Wiley Online Library
In this 30th anniversary issue review, we focus on the glucocorticoid modulation of limbic‐
prefrontocortical circuitry during stress‐coping. This action of the stress hormone is mediated …

Stress and memory retrieval: mechanisms and consequences

OT Wolf - Current Opinion in Behavioral Sciences, 2017 - Elsevier
Highlights•Effects of stress on memory retrieval last longer than initially expected.•They are
not restricted to hippocampal-based episodic memories.•They can have long-lasting …

For whom the bell (curve) tolls: Cortisol rapidly affects memory retrieval by an inverted U-shaped dose–response relationship

TM Schilling, M Kölsch, MF Larra, CM Zech… - …, 2013 - Elsevier
Stress and cortisol are generally considered to impair declarative memory retrieval, although
opposite results have also been reported. Dose-dependent effects and differences between …