Immune responses in bladder cancer-role of immune cell populations, prognostic factors and therapeutic implications

M Joseph, D Enting - Frontiers in oncology, 2019 - frontiersin.org
Immunosurveillance, which describes the immunologically mediated elimination of
transformed cells, has been widely accepted in the context of bladder cancer for many …

Prognostic and predictive value of tumor-infiltrating immune cells in urothelial cancer of the bladder

S van Wilpe, ECF Gerretsen, AG van der Heijden… - Cancers, 2020 - mdpi.com
Simple Summary There is substantial heterogeneity in the prognosis and responsiveness to
registered therapies in bladder cancer. Biomarkers that can accurately predict prognosis …

Identification of prognosis-related genes in the cervical cancer immune microenvironment

L Yang, Y Yang, M Meng, W Wang, S He, Y Zhao… - Gene, 2021 - Elsevier
Background Cervical cancer is the fourth most commonly diagnosed cancer in women
worldwide. The metastasis and invasion of this type of cancer are closely related to the …

DeepKEGG: a multi-omics data integration framework with biological insights for cancer recurrence prediction and biomarker discovery

W Lan, H Liao, Q Chen, L Zhu, Y Pan… - Briefings in …, 2024 - academic.oup.com
Deep learning-based multi-omics data integration methods have the capability to reveal the
mechanisms of cancer development, discover cancer biomarkers and identify pathogenic …

Poor lymphocyte infiltration to primary tumors in acral lentiginous melanoma and mucosal melanoma compared to cutaneous melanoma

Y Nakamura, Z Zhenjie, K Oya, R Tanaka… - Frontiers in …, 2020 - frontiersin.org
Recent clinical trials have demonstrated the efficacy of immune checkpoint inhibitors (ICIs)
for treating melanoma. However, these previous studies comprised mainly Caucasian …

Comprehensive analysis reveals a prognostic and therapeutic biomarker CD3D in the breast carcinoma microenvironment

Z Zhu, W Ye, X Wu, S Lin, J Xu, L Li, J Li… - Bioscience …, 2021 - portlandpress.com
Breast carcinoma (BRCA) is the most common carcinoma among women worldwide.
Despite the great progress achieved in early detection and treatment, morbidity and mortality …

CD3D is an independent prognostic factor and correlates with immune infiltration in gastric cancer

L Yuan, J Xu, Y Shi, Z Jin, Z Bao, P Yu, Y Wang… - Frontiers in …, 2022 - frontiersin.org
The protein encoded by CD3D is part of the T-cell receptor/CD3 complex (TCR/CD3
complex) and is involved in T-cell development and signal transduction. Previous studies …

[HTML][HTML] Significance of tumor-associated neutrophils, lymphocytes, and neutrophil-to-lymphocyte ratio in non-invasive and invasive bladder urothelial carcinoma

WA Hassan, AK ElBanna, N Noufal… - … of Pathology and …, 2023 - synapse.koreamed.org
Background Tumor-infiltrating neutrophils and lymphocytes play essential roles in promoting
or combating various neoplasms. This study aimed to investigate the association between …

Clinical impact of tumor-infiltrating lymphocytes and PD-L1-positive cells as prognostic and predictive biomarkers in urological malignancies and retroperitoneal …

M Miyake, S Hori, T Owari, Y Oda, Y Tatsumi, Y Nakai… - Cancers, 2020 - mdpi.com
Simple Summary Two host-dependent biological characteristics,“avoiding immune
destruction” and “tumor-promoting inflammation” have been added to cancer hallmarks in …

Therapeutic targeting of cancer stem cells in lung, head and neck, and bladder cancers

SE Mudra, P Sadhukhan, MT Ugurlu, S Alam… - Cancers, 2021 - mdpi.com
Simple Summary Effective cancer treatment hinges upon overcoming therapeutic resistance
mechanisms that allow for the continued proliferation of cancer cell subpopulations …