Axons are the slender, cable-like, up to meter-long projections of neurons that electrically
wire our brains and bodies. In spite of their challenging morphology, they usually need to be …

Axons are processes of neurons, up to a metre long, that form the essential biological cables
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …

The maintenance of axons for the lifetime of an organism requires an axonal cytoskeleton
that is robust but also flexible to adapt to mechanical challenges and to support plastic …

In addition to its well-established role in actin assembly, profilin 1 (PFN1) has been shown to
bind to tubulin and alter microtubule growth. However, whether PFN1's predominant control …

Comprehensive analysis of cellular dynamics during the process of morphogenesis is
fundamental to understanding the principles of animal development. Despite recent …

The formation and maintenance of microtubules requires their polymerisation, but little is
known about how this polymerisation is regulated in cells. Focussing on the essential …

Growth of the Drosophila oocyte requires transport of cytoplasmic materials from the
interconnected sister cells (nurse cells) through ring canals, the cytoplasmic bridges that …

Focal adhesions (FAs) connect inner workings of cell to the extracellular matrix to control cell
adhesion, migration and mechanosensing. Previous studies demonstrated that FAs contain …

Cortical collapse factors affect microtubule (MT) dynamics at the plasma membrane. They
play important roles in neurons, as suggested by inhibition of axon growth and regeneration …

The number of acquired or inherited conditions leading to axon degeneration (from now on
referred to as axonopathies) is vast. To diagnose patients, clinicians use a range of …