Aortic disease, including dissection, aneurysm, and rupture, carries significant morbidity and
mortality and is a notable cause of sudden cardiac death. Much of our knowledge regarding …

Aortic aneurysm is a common cardiovascular disease. Over time, the disease damages the
structural and functional integrity of the aorta, causing it to abnormally expand and …

Hereditary thoracic aorta diseases (HTADs) are a heterogeneous group of rare disorders
whose major manifestation is represented by aneurysm and/or dissection frequently located …

Background Accumulating evidence shows that dysregulation of intestinal flora is associated
with inflammatory skin diseases, specifically atopic dermatitis (AD), psoriasis (PSO), and …

Background Atopic dermatitis (AD) is a chronic inflammatory skin condition whose origins
remain unclear. Existing epidemiological evidence suggests that inflammation and immune …

Abdominal aortic aneurysm (AAA) is a common but life-threatening vascular condition in
men at an advanced age. However, the underlying mechanisms of age-increased incidence …

Background The effects of diabetes on the cardiac and aortic structure and function remain
unclear. Detecting and intervening these variations early is crucial for the prevention and …

Background The crucial role of inflammation in aortic aneurysm (AA) is gaining prominence,
while there is still a lack of key cytokines or targets for effective clinical translation. Methods …

Nonsyndromic sporadic thoracic aortic aneurysm (nssTAA) is characterized by diverse
genetic variants that may vary in different populations. Our aim was to identify clinically …

BACKGROUND: Ascending thoracic aortic dilation is a complex heritable trait that involves
modifiable and nonmodifiable risk factors. Polygenic scores (PGS) are increasingly used to …