What is a gene, post-ENCODE? History and updated definition

MB Gerstein, C Bruce, JS Rozowsky, D Zheng… - Genome …, 2007 - genome.cshlp.org
While sequencing of the human genome surprised us with how many protein-coding genes
there are, it did not fundamentally change our perspective on what a gene is. In contrast, the …

First steps in the analysis of prokaryotic pan-genomes

SS Costa, LC Guimarães, A Silva… - … and Biology Insights, 2020 - journals.sagepub.com
Pan-genome is defined as the set of orthologous and unique genes of a specific group of
organisms. The pan-genome is composed by the core genome, accessory genome, and …

[图书][B] Principles of plant genetics and breeding

G Acquaah - 2009 - books.google.com
Until recently, plant breeders have depended primarily on classicaltools to develop new and
improved products for producers andconsumers. However, with the advent of biotechnology …

A Draft Sequence of the Rice Genome (Oryza sativa L. ssp. indica)

J Yu, S Hu, J Wang, GKS Wong, S Li, B Liu, Y Deng… - science, 2002 - science.org
We have produced a draft sequence of the rice genome for the most widely cultivated
subspecies in China, Oryza sativa L. ssp. indica, by whole-genome shotgun sequencing …

AUGUSTUS: a web server for gene finding in eukaryotes

M Stanke, R Steinkamp, S Waack… - Nucleic acids …, 2004 - academic.oup.com
We present a www server for AUGUSTUS, a novel software program for ab initio gene
prediction in eukaryotic genomic sequences. Our method is based on a generalized Hidden …

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) … - Proceedings of the …, 2002 - National Acad Sciences
The National Institutes of Health Mammalian Gene Collection (MGC) Program is a
multiinstitutional effort to identify and sequence a cDNA clone containing a complete ORF for …

Complete sequencing and characterization of 21,243 full-length human cDNAs

T Ota, Y Suzuki, T Nishikawa, T Otsuki, T Sugiyama… - Nature …, 2004 - nature.com
As a base for human transcriptome and functional genomics, we created the “full-length long
Japan”(FLJ) collection of sequenced human cDNAs. We determined the entire sequence of …

Using geneid to identify genes

E Blanco, G Parra, R Guigó - Current protocols in …, 2007 - Wiley Online Library
This unit describes the usage of geneid, an efficient gene‐finding program that allows for the
analysis of large genomic sequences, including whole mammalian chromosomes. These …

Current methods of gene prediction, their strengths and weaknesses

C Mathé, MF Sagot, T Schiex, P Rouzé - Nucleic acids research, 2002 - academic.oup.com
While the genomes of many organisms have been sequenced over the last few years,
transforming such raw sequence data into knowledge remains a hard task. A great number …

The KA/KS ratio test for assessing the protein-coding potential of genomic regions: an empirical and simulation study

A Nekrutenko, KD Makova, WH Li - Genome research, 2002 - genome.cshlp.org
Comparative genomics is a simple, powerful way to increase the accuracy of gene
prediction. In this study, we show the utility of a simple test for the identification of protein …