Innate immunity is not only the first line of host defense against pathogenic infection, but also
the cornerstone of adaptive immune response. Upon pathogenic infection, pattern …

Infectious bursal disease virus (IBDV) affects immature B lymphocytes of the bursa of
Fabricius and may cause significant immunosuppression. It continues to be a leading cause …

The innate immune system, which senses invading pathogens, plays a critical role as the
first line of host defense. After recognition of foreign RNA ligands (eg, RNA viruses), host …

Recognition of viral RNAs by melanoma differentiation associated gene-5 (MDA5) initiates
chicken antiviral response by producing type I interferons. Our previous studies showed that …

Avian leukosis virus subgroup J (ALV-J) is an oncogenic retrovirus that has a similar
replication cycle to multiple viruses and therefore can be used as a model system for viral …

Infectious Bursal Disease Virus (IBDV) is the causative agent of an immunosuppressive
disease that affects domestic chickens (Gallus gallus) severely affecting poultry industry …

Heat stress induces immune dysfunction and cell death, but the mechanisms by which this
occurs are not fully understood. Therefore, the isobaric tags for relative and absolute …

Infectious bursal disease virus (IBDV) is one of the most important infectious diseases of
poultry around the world. Gut-associated lymphoid tissues (GALT) are the first line of …

Avian Tembusu virus (ATMUV) is a newly emerged flavivirus that belongs to the Ntaya virus
group. ATMUV is a highly pathogenic virus causing significant economic loss to the Chinese …

MicroRNAs are small noncoding RNAs playing an important role in host response to
pathogenic infection. Here we show that IBDV infection induced the demethylation of the pre …