Growth factors play a crucial role in regulating a broad variety of biological processes and
are regarded as powerful therapeutic agents in tissue engineering and regenerative …

Titanium (Ti) is broadly used for clinical purposes in various medical fields related to bone
repair because of its favorable mechanical properties and its ability to osseointegrate in host …

Joint replacement is a major orthopaedic procedure used to treat joint osteoarthritis. Aseptic
loosening and infection are the two most significant causes of prosthetic implant failure. The …

Xenotransplantation of patient-derived samples in mouse models has been instrumental in
depicting the role of hematopoietic stem and progenitor cells in the establishment as well as …

A natural long-chain polymer, chitin is the main component of the cell walls of fungi, the
exoskeletons of arthropods (including crustaceans and insects), the radulas of mollusks, and …

The review encompasses state-of-the-art strategies for design and fabrication of smart
biomaterials for tissue engineering. The focus of the work is mainly put on metallic …

The treatment of large osseous defects remains a challenging clinical problem in orthopedic
surgery. Particularly, strategies to control the appropriate degradation rate adapting to the …

A simple method for the functionalization of a common implant material (Ti6Al4V) with
biodegradable, drug loaded chitosan-tripolyphosphate (CS-TPP) nanoparticles is …

In this study, a silica xerogel-chitosan hybrid is utilized as a coating material to incorporate
bone morphogenic protein-2 (BMP-2) on a porous hydroxyapatite (HA) scaffold for bone …

A variety of biomaterials have been introduced as potential substrates for cartilage repair.
One such candidate is chitosan, which shares some characteristics with glycosaminoglycan …