Common symptoms of overt hypothyroidism are non-specific and include fatigue, lethargy,
and dry skin. Although the diagnosis is considered to be straightforward, no single symptom …

Subclinical hypothyroidism, which is defined as a thyroid-stimulating hormone concentration
higher than the reference range (generally 4· 5 mIU/L or higher) with normal free thyroxine …

Importance Associations between modifiable chronic health conditions (CHCs), social
determinants of health, and late mortality (defined as death occurring≥ 5 years after …

Context Benefits of thyroid hormone therapy on mortality in adults with subclinical
hypothyroidism remain undetermined. Objective To summarize the impact of thyroid …

Background Subclinical hypothyroidism (SCH) is an asymptomatic condition associated with
increased thyroid‐stimulating hormone (TSH)> 4 mIU/L with normal thyroxine (T4) and …

Background Although hypothyroidism is associated with various comorbidities, its
relationship with increased all-cause mortality remains controversial. The aim of this …

Background Hypothyroidism is associated with impaired glomerular filtration rate (GFR), a
recognized cardiovascular disease (CVD), and mortality risk factor. In older adults, this …

Primary hypothyroidism is a common disorder in clinical practice. The management of most
cases of hypothyroidism is usually straightforward, but the best approach in some special …

Objective This study aims to determine whether elevated endogenous thyrotropin levels
contribute to an increased risk of adverse outcomes, such as all-cause mortality in older …

甲状腺疾病是一种临床上常见的内分泌疾病, 其病因机制复杂多样. 目前关于甲状腺疾病的研究
主要局限于临床上的药效评价, 对其发病机制研究较少, 因此甲状腺疾病动物模型的建立对分析 …