The effects of protein corona on in vivo fate of nanocarriers

Q Xiao, M Zoulikha, M Qiu, C Teng, C Lin, X Li… - Advanced Drug Delivery …, 2022 - Elsevier
With the emerging advances in utilizing nanocarriers for biomedical applications, a
molecular-level understanding of the in vivo fate of nanocarriers is necessary. After …

Nanoparticle protein corona: from structure and function to therapeutic targeting

G Bashiri, MS Padilla, KL Swingle, SJ Shepherd… - Lab on a Chip, 2023 - pubs.rsc.org
Nanoparticle (NP)-based therapeutics have ushered in a new era in translational medicine.
However, despite the clinical success of NP technology, it is not well-understood how NPs …

Physiological barriers and strategies of lipid‐based nanoparticles for nucleic acid drug delivery

M Hu, X Li, Z You, R Cai, C Chen - Advanced Materials, 2024 - Wiley Online Library
Lipid‐based nanoparticles (LBNPs) are currently the most promising vehicles for nucleic
acid drug (NAD) delivery. Although their clinical applications have achieved success, the …

Bacterial outer membrane vesicles as potential biological nanomaterials for antibacterial therapy

W Huang, L Meng, Y Chen, Z Dong, Q Peng - Acta biomaterialia, 2022 - Elsevier
Antibiotic therapy is one of the most important approaches against bacterial infections.
However, the improper use of antibiotics and the emergence of drug resistance have …

Nanomaterials-based photosensitizers and delivery systems for photodynamic cancer therapy

XT Yu, SY Sui, YX He, CH Yu, Q Peng - Biomaterials Advances, 2022 - Elsevier
The increasing cancer morbidity and mortality requires the development of high-efficiency
and low-toxicity anticancer approaches. In recent years, photodynamic therapy (PDT) has …

Pulmonary delivery nanomedicines towards circumventing physiological barriers: Strategies and characterization approaches

W Wang, Z Huang, Y Huang, X Zhang, J Huang… - Advanced Drug Delivery …, 2022 - Elsevier
Pulmonary delivery of nanomedicines is very promising in lung local disease treatments
whereas several physiological barriers limit its application via the interaction with inhaled …

Inhalable biomimetic protein corona-mediated nanoreactor for self-amplified lung adenocarcinoma ferroptosis therapy

W Wang, F Fu, Z Huang, W Wang, M Chen, X Yue… - ACS …, 2022 - ACS Publications
Ferroptosis therapy by catalyzing the Fenton reaction has emerged as a promising tumor
elimination strategy for lung adenocarcinoma (ADC). However, the unsatisfactory Fenton …

Biological features of nanoparticles: protein corona formation and interaction with the immune system

S Panico, S Capolla, S Bozzer, G Toffoli, M Dal Bo… - Pharmaceutics, 2022 - mdpi.com
Nanoparticles (NPs) are versatile candidates for nanomedical applications due to their
unique physicochemical properties. However, their clinical applicability is hindered by their …

Microfluidic assembly of “Turtle-Like” shaped solid lipid nanoparticles for lysozyme delivery

F Sommonte, I Arduino, RM Iacobazzi, M Tiboni… - International Journal of …, 2023 - Elsevier
After two decades of research in the field of nanomedicine, nanoscale delivery systems for
biologicals are becoming clinically relevant tools. Microfluidic-based fabrication processes …

Microfluidics for nano-drug delivery systems: from fundamentals to industrialization

H Zhang, J Yang, R Sun, S Han, Z Yang… - Acta Pharmaceutica Sinica …, 2023 - Elsevier
In recent years, owing to the miniaturization of the fluidic environment, microfluidic
technology offers unique opportunities for the implementation of nano drug delivery systems …