Clustered miRNAs and their role in biological functions and diseases
MicroRNAs (miRNAs) are endogenous, small non‐coding RNAs known to regulate
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
expression of protein‐coding genes. A large proportion of miRNAs are highly conserved …
[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
[HTML][HTML] Radioresistance in Glioblastoma and the Development of Radiosensitizers
Simple Summary Numerous mechanisms of glioblastoma (GBM) radioresistance have been
identified but have not yet resulted in development of effective radiosensitizer that can …
identified but have not yet resulted in development of effective radiosensitizer that can …
[HTML][HTML] miR-221/222 as biomarkers and targets for therapeutic intervention on cancer and other diseases: A systematic review
Among deregulated microRNAs (miRs) in human malignancies, miR-221 has been widely
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
investigated for its oncogenic role and as a promising biomarker. Moreover, recent evidence …
MicroRNAs in glioblastoma multiforme pathogenesis and therapeutics
A Shea, V Harish, Z Afzal, J Chijioke, H Kedir… - Cancer …, 2016 - Wiley Online Library
Glioblastoma multiforme (GBM) is the most common and lethal cancer of the adult brain,
remaining incurable with a median survival time of only 15 months. In an effort to identify …
remaining incurable with a median survival time of only 15 months. In an effort to identify …
[HTML][HTML] Potential value of miR-221/222 as diagnostic, prognostic, and therapeutic biomarkers for diseases
J Song, Y Ouyang, J Che, X Li, Y Zhao, K Yang… - Frontiers in …, 2017 - frontiersin.org
microRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by base
pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the …
pairing with their target messenger RNAs. Dysregulation of miRNAs is involved in the …
[HTML][HTML] Liquid biopsy in glioblastoma: opportunities, applications and challenges
A Saenz-Antoñanzas, J Auzmendi-Iriarte… - Cancers, 2019 - mdpi.com
Liquid biopsy represents a minimally invasive procedure that can provide similar information
from body fluids to what is usually obtained from a tissue biopsy sample. Its implementation …
from body fluids to what is usually obtained from a tissue biopsy sample. Its implementation …
Liquid biopsy in glioblastoma management: from current research to future perspectives
L Gatto, E Franceschi, V Di Nunno, A Tosoni… - The …, 2021 - academic.oup.com
Glioblastoma (GBM) is the most common primary tumor of the central nervous system.
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …
Arising from neuroepithelial glial cells, GBM is characterized by invasive behavior, extensive …
[HTML][HTML] Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma
F Felicetti, A De Feo, C Coscia, R Puglisi… - Journal of translational …, 2016 - Springer
Background Growing evidence is showing that metastatic cell populations are able to
transfer their characteristics to less malignant cells. Exosomes (EXOs) are membrane …
transfer their characteristics to less malignant cells. Exosomes (EXOs) are membrane …
[HTML][HTML] Role of microRNAs in glioblastoma
Glioblastoma is the most common and aggressive primary human brain cancer. MicroRNAs
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …
(miRNAs) are a set of small endogenous non-coding RNA molecules which play critical …