Circulating blood is filtered across the glomerular barrier to form an ultrafiltrate of plasma in
the Bowman's space. The volume of glomerular filtration adjusted by time is defined as the …

Significance: Intrarenal oxidative stress plays a critical role in the initiation and progression
of diabetic kidney disease (DKD). Enhanced oxidative stress results from overproduction of …

Regulated production of reactive oxygen species (ROS)/reactive nitrogen species (RNS)
adequately balanced by antioxidant systems is a prerequisite for the participation of these …

At present, diabetic kidney disease affects about 15–25% of type 1 and 30–40% of type 2
diabetic patients. Several decades of extensive research has elucidated various pathways to …

Metabolic syndrome and oxidative stress are common complications of type 2 diabetes
mellitus. The present study was designed to determine whether resveratrol, a widely used …

OBJECTIVES: Oxidative stress is considered to be a unifying link between diabetes mellitus
(DM) and its complications including nephropathy. The aim of the present study was to …

Diabetic nephropathy (DN) is one of the major microvascular complications of diabetes and
it is defined as a rise in the urinary albumin excretion (UAE) rate and abnormal renal …

Background Type 2 diabetes mellitus, characterized by peripheral insulin resistance, is a
major lifestyle disorder of the 21 st Century. Raw garlic homogenate has been reported to …

Background Altered serum nitric oxide (NO) levels in patients with diabetes mellitus (DM)
have been reported by different studies; however, results are still controversial. Until this …

Accelerated atherosclerosis and microvascular complications are the leading causes of
coronary heart disease, end-stage renal failure, acquired blindness and a variety of …