[HTML][HTML] Health equity in the implementation of genomics and precision medicine: A public health imperative

MJ Khoury, S Bowen, WD Dotson, E Drzymalla… - Genetics in …, 2022 - Elsevier
Recent reviews have emphasized the need for a health equity agenda in genomics
research. To ensure that genomic discoveries can lead to improved health outcomes for all …

Familial hypercholesterolaemia: evolving knowledge for designing adaptive models of care

GF Watts, SS Gidding, P Mata, J Pang… - Nature Reviews …, 2020 - nature.com
Optimal care for familial hypercholesterolaemia (FH) requires patient-centred management,
multidisciplinary teamwork, involvement of primary care practitioners, patient networks …

Association of monogenic vs polygenic hypercholesterolemia with risk of atherosclerotic cardiovascular disease

M Trinder, GA Francis, LR Brunham - JAMA cardiology, 2020 - jamanetwork.com
Importance Monogenic familial hypercholesterolemia (FH) is associated with lifelong
elevations in low-density lipoprotein cholesterol (LDL-C) levels and increased risk of …

How to optimize the adherence to a guideline-directed medical therapy in the secondary prevention of cardiovascular diseases: a clinical consensus statement from …

RFE Pedretti, D Hansen, M Ambrosetti… - European journal of …, 2023 - academic.oup.com
A key factor to successful secondary prevention of cardiovascular disease (CVD) is optimal
patient adherence to treatment. However, unsatisfactory rates of adherence to treatment for …

Nonadherence to lipid‐lowering therapy and strategies to improve adherence in patients with atherosclerotic cardiovascular disease

NR Desai, M Farbaniec, DG Karalis - Clinical Cardiology, 2023 - Wiley Online Library
Despite the availability of effective therapies that lower low‐density lipoprotein cholesterol
(LDL‐C) levels in patients with atherosclerotic cardiovascular disease, many eligible …

Women living with familial hypercholesterolemia: challenges and considerations surrounding their care

S Balla, EP Ekpo, KA Wilemon, JW Knowles… - Current atherosclerosis …, 2020 - Springer
Abstract Purpose of Review To highlight the gender-based differences in presentation and
disparities in care for women with familial hypercholesterolemia (FH). Recent Findings …

LDL-C target attainment in secondary prevention of ASCVD in the United States: barriers, consequences of nonachievement, and strategies to reach goals

J Underberg, PP Toth, F Rodriguez - Postgraduate Medicine, 2022 - Taylor & Francis
Atherosclerotic cardiovascular disease (ASCVD) is the leading cause of death in the United
States. Elevated low-density lipoprotein cholesterol (LDL-C) is a major causal risk factor for …

Reducing cardiovascular risk in patients with familial hypercholesterolemia: Risk prediction and lipid management

MH Miname, RD Santos - Progress in cardiovascular diseases, 2019 - Elsevier
Familial hypercholesterolemia (FH) is a frequent genetic disorder characterized by elevated
low-density lipoprotein (LDL)-cholesterol (LDL-C) levels and early onset of atherosclerotic …

[HTML][HTML] LDL cholesterol targets rarely achieved in familial hypercholesterolemia patients: A sex and gender-specific analysis

MM Schreuder, S Hamkour, KE Siegers, KB Holven… - Atherosclerosis, 2023 - Elsevier
Background and aims Despite lipid lowering therapy (LLT), reaching LDL-C targets in
patients with familial hypercholesterolemia (FH) remains challenging. Our aim was to …

Streamlining and reimagining prior authorization under value-based contracts: a call to action from the value in healthcare initiative's prior authorization learning …

MA Psotka, EA Singletary, WK Bleser… - … Quality and Outcomes, 2020 - Am Heart Assoc
Utilization management strategies, including prior authorization, are commonly used to
facilitate safe and guideline-adherent provision of new, individualized, and potentially costly …