[HTML][HTML] Challenges of advanced hepatocellular carcinoma

S Colagrande, AL Inghilesi, S Aburas… - World journal of …, 2016 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is an aggressive malignancy, resulting as the third cause
of death by cancer each year. The management of patients with HCC is complex, as both the …

[Retracted] Hepatocellular Carcinoma: Novel Molecular Targets in Carcinogenesis for Future Therapies

G Bertino, S Demma, A Ardiri, M Proiti… - BioMed research …, 2014 - Wiley Online Library
Background. Hepatocellular carcinoma is one of the most common and lethal malignant
tumors worldwide. Over the past 15 years, the incidence of HCC has more than doubled …

[PDF][PDF] Lenvatinib may drastically change the treatment landscape of hepatocellular carcinoma

M Kudo - Liver cancer, 2018 - karger.com
Since then, several first-line clinical trials have been conducted with the aim of developing
molecular targeted agents showing better efficacy or safety than sorafenib [3](Table 1). A …

Inter-operator variability and source of errors in tumour response assessment for hepatocellular carcinoma treated with sorafenib

F Tovoli, M Renzulli, G Negrini, S Brocchi… - European …, 2018 - Springer
Objectives To assess the inter-operator concordance and the potential sources of
discordance in defining response to sorafenib in hepatocellular carcinoma (HCC). Methods …

Lenvatinib or Sorafenib Treatment Causing a Decrease in Skeletal Muscle Mass, an Independent Prognostic Factor in Hepatocellular Carcinoma: A Survival Analysis …

K Imai, K Takai, S Unome, T Miwa, T Hanai… - Cancers, 2023 - mdpi.com
Simple Summary Skeletal muscle depletion is one of the established prognostic factors for
hepatocellular carcinoma (HCC). This study clearly demonstrated that skeletal muscle mass …

mRECIST to predict survival in advanced hepatocellular carcinoma: analysis of two randomised phase II trials comparing nintedanib vs sorafenib

T Meyer, DH Palmer, AL Cheng, J Hocke… - Liver …, 2017 - Wiley Online Library
Abstract Background & Aims Response Evaluation Criteria in Solid Tumors (RECIST) has
been shown to be a poor surrogate for survival benefit with targeted therapy in advanced …

Rapid depletions of subcutaneous fat mass and skeletal muscle mass predict worse survival in patients with hepatocellular carcinoma treated with sorafenib

K Imai, K Takai, T Miwa, D Taguchi, T Hanai… - Cancers, 2019 - mdpi.com
The aim of this study was to investigate whether rapid depletions of fat mass and skeletal
muscle mass predict mortality in hepatocellular carcinoma (HCC) patients treated with …

Skeletal muscle depletion predicts the prognosis of patients with hepatocellular carcinoma treated with sorafenib

K Imai, K Takai, T Hanai, T Ideta, T Miyazaki… - International journal of …, 2015 - mdpi.com
The aim of this study was to determine whether skeletal muscle depletion predicts the
prognosis of patients with hepatocellular carcinoma (HCC) that is being treated with …

[HTML][HTML] Advanced hepatocellular carcinoma and sorafenib: Diagnosis, indications, clinical and radiological follow-up

S Colagrande, F Regini, GG Taliani… - World journal of …, 2015 - ncbi.nlm.nih.gov
Advanced stage hepatocellular carcinoma (HCC) is a category of disease defined by
radiological, clinical and hepatic function parameters, comprehending a wide range of …

Response evaluation criteria in cancer of the liver version 6 (response evaluation criteria in cancer of the liver 2021 revised version)

M Kudo, M Ikeda, K Ueshima, M Sakamoto… - Hepatology …, 2022 - Wiley Online Library
Abstract Response Evaluation Criteria in Solid Tumors (RECIST) is inappropriate to assess
the direct effects of treatment on hepatocellular carcinoma (HCC) by locoregional therapies …