Apoptotic bodies for advanced drug delivery and therapy
M Zhou, YJ Li, YC Tang, XY Hao, WJ Xu… - Journal of Controlled …, 2022 - Elsevier
Extracellular vesicles (EVs) have emerged as promising candidates for multiple biomedical
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …
applications. Major types of EVs include exosomes, microvesicles, and apoptotic bodies …
The critical role of apoptosis in mesenchymal stromal cell therapeutics and implications in homeostasis and normal tissue repair
C Giacomini, C Granéli, R Hicks, F Dazzi - Cellular & Molecular …, 2023 - nature.com
Mesenchymal stromal cells (MSCs) have been extensively tested for the treatment of
numerous clinical conditions and have demonstrated good safety but mixed efficacy …
numerous clinical conditions and have demonstrated good safety but mixed efficacy …
Apoptotic vesicles restore liver macrophage homeostasis to counteract type 2 diabetes
C Zheng, B Sui, X Zhang, J Hu, J Chen… - Journal of …, 2021 - Wiley Online Library
Apoptosis is a naturally occurring process generating plenty of apoptotic vesicles (apoVs),
but the feature, fate and function of apoVs remain largely unknown. Notably, as an …
but the feature, fate and function of apoVs remain largely unknown. Notably, as an …
Apoptotic bodies: mechanism of formation, isolation and functional relevance
JP Santavanond, SF Rutter, GK Atkin-Smith… - New Frontiers …, 2021 - Springer
In the final stages of apoptosis, apoptotic cells can generate a variety of membrane-bound
vesicles known as apoptotic extracellular vesicles (ApoEVs). Apoptotic bodies (ApoBDs), a …
vesicles known as apoptotic extracellular vesicles (ApoEVs). Apoptotic bodies (ApoBDs), a …
Extracellular vesicle-associated proteins in tissue repair
MT Roefs, JPG Sluijter, P Vader - Trends in cell biology, 2020 - cell.com
The administration of (stem) cell-derived extracellular vesicles (EVs) promotes tissue repair
through management of different inflammatory, proliferative and remodeling processes in …
through management of different inflammatory, proliferative and remodeling processes in …
[HTML][HTML] In situ delivery of apoptotic bodies derived from mesenchymal stem cells via a hyaluronic acid hydrogel: a therapy for intrauterine adhesions
L Xin, C Wei, X Tong, Y Dai, D Huang, J Chen, L Ma… - Bioactive materials, 2022 - Elsevier
Stem cell-based and stem cell-derived exosome-based therapies have shown promising
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
potential for endometrial regeneration and the clinical treatment of intrauterine adhesions …
Apoptotic bodies: bioactive treasure left behind by the dying cells with robust diagnostic and therapeutic application potentials
L Yu, G Zhu, Z Zhang, Y Yu, L Zeng, Z Xu… - Journal of …, 2023 - Springer
Apoptosis, a form of programmed cell death, is essential for growth and tissue homeostasis.
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …
Apoptotic bodies (ApoBDs) are a form of extracellular vesicles (EVs) released by dying cells …
Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles
S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …
Targeting efferocytosis in inflammaging
IKH Poon, KS Ravichandran - Annual review of pharmacology …, 2024 - annualreviews.org
Rapid removal of apoptotic cells by phagocytes, a process known as efferocytosis, is key for
the maintenance of tissue homeostasis, the resolution of inflammation, and tissue repair …
the maintenance of tissue homeostasis, the resolution of inflammation, and tissue repair …
Extracellular vesicles arising from apoptosis: Forms, functions, and applications
CD Gregory, MP Rimmer - The Journal of Pathology, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed subcellular bodies produced by most,
if not all cells. Research over the last two decades has recognised the importance of EVs in …
if not all cells. Research over the last two decades has recognised the importance of EVs in …