Cadmium as a testicular toxicant: A Review
JK Bhardwaj, H Panchal, P Saraf - Journal of Applied …, 2021 - Wiley Online Library
Cadmium (Cd) is a toxic heavy metal with no known biological functions in the human body.
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …
Due to a considerably long biological half‐life and very low rate of excretion, accumulation …
Ameliorating effects of natural antioxidant compounds on female infertility: a review
JK Bhardwaj, H Panchal, P Saraf - Reproductive sciences, 2021 - Springer
The prevalence of female infertility cases has been increasing at a frightening rate, affecting
approximately 48 million women across the world. However, oxidative stress has been …
approximately 48 million women across the world. However, oxidative stress has been …
New approach methodologies for exposure science
Chemical risk assessment relies on knowledge of hazard, the dose–response relationship,
and exposure to characterize potential risks to public health and the environment. A …
and exposure to characterize potential risks to public health and the environment. A …
Pesticides induced oxidative stress and female infertility: a review
JK Bhardwaj, M Mittal, P Saraf, P Kumari - Toxin Reviews, 2018 - Taylor & Francis
Oxidative stress impairs the female reproductive physiology by altering the affectivity of
antioxidant defense system in the individual. Several toxicants mainly pesticides alters this …
antioxidant defense system in the individual. Several toxicants mainly pesticides alters this …
Cadmium as an ovarian toxicant: A review
JK Bhardwaj, P Bikal… - Journal of Applied …, 2024 - Wiley Online Library
Cadmium (Cd) is a ubiquitous heavy metal toxicant with no biological function in the human
body. Considerably, because of its long biological half‐life and very low excretion rate, Cd is …
body. Considerably, because of its long biological half‐life and very low excretion rate, Cd is …
N6-methyladenosine demethylase FTO induces the dysfunctions of ovarian granulosa cells by upregulating flotillin 2
L Zhou, X Han, W Li, N Wang, L Yao, Y Zhao… - Reproductive …, 2022 - Springer
Polycystic ovarian syndrome (PCOS) is often accompanied by overweight/obesity and
insulin resistance. The dysfunctions of ovarian granulosa cells (GCs) are closely linked with …
insulin resistance. The dysfunctions of ovarian granulosa cells (GCs) are closely linked with …
Synthesis, regulatory factors, and signaling pathways of estrogen in the ovary
C Xiao, J Wang, C Zhang - Reproductive Sciences, 2023 - Springer
New insights have been thrown for understanding the significant role of estrogen on various
systems of humans. Increasing evidences have determined the significant roles of estrogen …
systems of humans. Increasing evidences have determined the significant roles of estrogen …
N‐Acetyl‐cysteine mediated inhibition of spermatogonial cells apoptosis against malathion exposure in testicular tissue
JK Bhardwaj, P Saraf, P Kumari… - … of Biochemical and …, 2018 - Wiley Online Library
Toxicological studies so far suggest that excessive use of malathion, an organophosphate
insecticide, causes serious ill‐effects in mammalian reproductive physiology. The present …
insecticide, causes serious ill‐effects in mammalian reproductive physiology. The present …
Reproductive toxicity by exposure to low concentrations of pesticides in Caenorhabditis elegans
A Moya, D Tejedor, M Manetti, A Clavijo, E Pagano… - Toxicology, 2022 - Elsevier
In view of the recurrent applications of pesticides in agricultural producing countries, the
increased presence of these substances in the environment raise a demand for the …
increased presence of these substances in the environment raise a demand for the …
Effective attenuation of glyphosate‐induced oxidative stress and granulosa cell apoptosis by vitamins C and E in caprines
JK Bhardwaj, M Mittal, P Saraf - Molecular reproduction and …, 2019 - Wiley Online Library
Pesticides are known to cause a wide range of reproductive problems that possess
degenerative effects on mammalian fertility. Glyphosate (GLP), a broad‐spectrum …
degenerative effects on mammalian fertility. Glyphosate (GLP), a broad‐spectrum …