Bioinspired nanotopographical design of drug delivery systems
JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …
Advanced particulate carrier-mediated technologies for nasal drug delivery
VP Chavda, G Jogi, N Shah, MN Athalye… - Journal of Drug Delivery …, 2022 - Elsevier
Nasal drug delivery has been employed as an alternate and convenient route for the
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …
systemic availability of pharmaceuticals, particularly for potent therapeutics. This is owing to …
Fabrication of chitosan/polyvinylpyrrolidone hydrogel scaffolds containing PLGA microparticles loaded with dexamethasone for biomedical applications
One of the most effective approaches for treatment of chronic rhinosinusitis is the use of
hydrogel scaffolds with the sustained release of a given required drug. With this in mind, first …
hydrogel scaffolds with the sustained release of a given required drug. With this in mind, first …
Enhancing immunogenicity of antigens through sustained intradermal delivery using chitosan microneedles with a patch-dissolvable design
MC Chen, KY Lai, MH Ling, CW Lin - Acta biomaterialia, 2018 - Elsevier
Reducing the dosage required for vaccination is highly desirable, particularly in cases of
epidemic emergencies. This study evaluated the potential of a chitosan microneedle (MN) …
epidemic emergencies. This study evaluated the potential of a chitosan microneedle (MN) …
How to characterize a nasal product. The state of the art of in vitro and ex vivo specific methods
Nasal delivery offers many benefits over other conventional routes of delivery (eg oral or
intravenous administration). Benefits include, among others, a fast onset of action, non …
intravenous administration). Benefits include, among others, a fast onset of action, non …
Protein stabilization of ITF2 by NF-κB prevents colitis-associated cancer development
M Lee, YS Kim, S Lim, SH Shin, I Kim, J Kim… - Nature …, 2023 - nature.com
Chronic colonic inflammation is a feature of cancer and is strongly associated with
tumorigenesis, but its underlying molecular mechanisms remain poorly understood …
tumorigenesis, but its underlying molecular mechanisms remain poorly understood …
Mucoadhesive electrospun nanofibers for drug delivery systems: applications of polymers and the parameters' roles
GL Pérez-González, LJ Villarreal-Gómez… - International journal …, 2019 - Taylor & Francis
Electrospun nanofibers have been widely studied for many medical applications. They can
be designed with specific features, including mucoadhesive properties. This review …
be designed with specific features, including mucoadhesive properties. This review …
Phenylboronic acid-tethered chondroitin sulfate-based mucoadhesive nanostructured lipid carriers for the treatment of dry eye syndrome
Dry eye syndrome is a common eye disease that affects many people worldwide. It is usually
treated with eye drops, which has low bioavailability owing to rapid clearance from the …
treated with eye drops, which has low bioavailability owing to rapid clearance from the …
[HTML][HTML] DEP-induced ZEB2 promotes nasal polyp formation via epithelial-to-mesenchymal transition
M Lee, S Lim, YS Kim, R Khalmuratova, SH Shin… - Journal of Allergy and …, 2022 - Elsevier
Background Diesel exhaust particles (DEPs) are associated with the prevalence and
exacerbation of allergic respiratory diseases, including allergic rhinitis and allergic asthma …
exacerbation of allergic respiratory diseases, including allergic rhinitis and allergic asthma …
Sodium hyaluronate/chitosan composite microneedles as a single-dose intradermal immunization system
YH Chiu, MC Chen, SW Wan - Biomacromolecules, 2018 - ACS Publications
Enhancing the immune response to vaccines and minimizing the need for repeated
inoculations remain a challenge in clinical vaccination. This study developed a composite …
inoculations remain a challenge in clinical vaccination. This study developed a composite …