Long non-coding RNAs (lncRNAs) represent a significant population of the human
transcriptome. Many lncRNAs exhibit cell-and/or tissue/tumor-specific expression, making …

Non-coding RNAs represent a significant proportion of the human genome. After having
been considered as 'junk'for a long time, non-coding RNAs are now well established as …

Clinical advances enable the prenatal diagnosis of genetic diseases that are candidates for
gene and enzyme therapies such as messenger RNA (mRNA)–mediated protein …

Because of high specificity and easy detection in the tissues, serum, plasma, urine and
saliva, interest in exploring the potential of long non‐coding RNAs (lncRNAs) in cancer …

Polyethlyenimine (PEI) was introduced 1995 as a cationic polymer for nucleic acid delivery.
PEI and its derivatives are extensively used in basic research and as reference formulations …

Since the elucidation of the molecular structure of nucleic acids and understanding of their
role in encoding and translating genetic information into biological function, 1 the knowledge …

With the advent of next generation sequencing methods and progress in transcriptome
analysis, it became obvious that the human genome contains much more than just protein …

The nuclear paraspeckle assembly transcript 1 (NEAT1, a long non-coding RNA) is
frequently overexpressed in human tumors, and higher NEAT1 expression is correlated with …

Nanocarriers offer unique possibilities to overcome cellular barriers in order to improve the
delivery of various drugs and drug candidates, including the promising therapeutic …

Gene therapy offers great opportunities for the treatment of severe diseases including
cancer. In recent years the design of synthetic carriers for nucleic acid delivery has become …