Attenuated innate immunity in embryonic stem cells and its implications in developmental biology and regenerative medicine
Embryonic stem cells (ESCs) represent a promising cell source for regenerative medicine.
Intensive research over the past 2 decades has led to the feasibility of using ESC …
Intensive research over the past 2 decades has led to the feasibility of using ESC …
The underdeveloped innate immunity in embryonic stem cells: The molecular basis and biological perspectives from early embryogenesis
YL Guo - American Journal of Reproductive Immunology, 2019 - Wiley Online Library
Embryonic stem cells (ESCs) have been intensively studied as a promising cell source for
regenerative medicine. The rapid advancements in the field have not only proven the …
regenerative medicine. The rapid advancements in the field have not only proven the …
Dicer represses the interferon response and the double-stranded RNA-activated protein kinase pathway in mouse embryonic stem cells
Recent studies have demonstrated that embryonic stem cells (ESCs) are deficient in
expressing type I interferons (IFN), the cytokines that play key roles in antiviral responses …
expressing type I interferons (IFN), the cytokines that play key roles in antiviral responses …
[HTML][HTML] Antiviral responses in mouse embryonic stem cells: differential development of cellular mechanisms in type I interferon production and response
Antiviral Responses in Mouse Embryonic Stem Cells - PMC Back to Top Skip to main content
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …
NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main …
The molecular basis for the lack of inflammatory responses in mouse embryonic stem cells and their differentiated cells
We reported previously that mouse embryonic stem cells do not have a functional IFN-based
antiviral mechanism. The current study extends our investigation to the inflammatory …
antiviral mechanism. The current study extends our investigation to the inflammatory …
Development of antiviral innate immunity during in vitro differentiation of mouse embryonic stem cells
The innate immunity of embryonic stem cells (ESCs) has recently emerged as an important
issue in ESC biology and in ESC-based regenerative medicine. We have recently reported …
issue in ESC biology and in ESC-based regenerative medicine. We have recently reported …
Utilization of different anti‐viral mechanisms by mammalian embryonic stem cells and differentiated cells
YL Guo - Immunology and cell biology, 2017 - Wiley Online Library
Embryonic stem cells (ESCs) have received tremendous attention because of their potential
applications in regenerative medicine. Over the past two decades, intensive research has …
applications in regenerative medicine. Over the past two decades, intensive research has …
[HTML][HTML] The Generation of Genetically Engineered Human Induced Pluripotent Stem Cells Overexpressing IFN-β for Future Experimental and Clinically Oriented …
O Sheveleva, E Protasova, E Grigor'eva… - International Journal of …, 2024 - mdpi.com
Induced pluripotent stem cells (iPSCs) can be generated from various adult cells, genetically
modified and differentiated into diverse cell populations. Type I interferons (IFN-Is) have …
modified and differentiated into diverse cell populations. Type I interferons (IFN-Is) have …
Dicer and PKR as novel regulators of embryonic stem cell fate and antiviral innate immunity
Embryonic stem cells (ESCs) represent a unique cell population in the blastocyst stage
embryo. They have been intensively studied as a promising cell source for regenerative …
embryo. They have been intensively studied as a promising cell source for regenerative …
Pluripotent stem cells are insensitive to the cytotoxicity of TNFα and IFNγ
Recent studies have demonstrated that embryonic stem cells (ESCs) have an
underdeveloped innate immune system, but the biological implications of this finding are …
underdeveloped innate immune system, but the biological implications of this finding are …