Structural dynamics in proteins induced by and probed with X-ray free-electron laser pulses
X-ray free-electron lasers (XFELs) enable crystallographic structure determination beyond
the limitations imposed upon synchrotron measurements by radiation damage. The need for …
the limitations imposed upon synchrotron measurements by radiation damage. The need for …
Hybrid plasma/molecular-dynamics approach for efficient XFEL radiation damage simulations
X-ray free-electron laser pulses initiate a complex series of changes to the electronic and
nuclear structure of matter on femtosecond timescales. These damage processes include …
nuclear structure of matter on femtosecond timescales. These damage processes include …
Effect of radiation damage and illumination variability on signal-to-noise ratio in X-ray free-electron laser single-particle imaging
The deterioration of both the signal-to-noise ratio and the spatial resolution in the electron-
density distribution reconstructed from diffraction intensities collected at different orientations …
density distribution reconstructed from diffraction intensities collected at different orientations …
[PDF][PDF] Recovery of undamaged electron-density maps in the presence of damage-induced partial coherence in single-particle imaging
Resolving the electronic structure of single biological molecules in their native state was
among the primary motivations behind X-ray free-electron lasers. The ultra-short pulses they …
among the primary motivations behind X-ray free-electron lasers. The ultra-short pulses they …