Adenosine 5′-monophosphate (AMP)-activated protein kinase (AMPK) is a key player in
regulating energy metabolism, placing it at the center stage in studies of diabetes and …

The biological clocks of the circadian timing system coordinate cellular and physiological
processes and synchronizes these with daily cycles, feeding patterns also regulates …

Maternal high-fat (HF) diet throughout gestation and suckling has long-term consequences
on the offspring's metabolic phenotype. Here we determine the relative contribution of pre-or …

All life forms on earth require a continuous input and monitoring of carbon and energy
supplies. The AMP‐activated kinase (AMPK)/sucrose nonfermenting1 (SNF1)/Snf1‐related …

Dietary restriction (DR) without malnutrition is widely regarded to be a universal mechanism
for prolonging lifespan. It is generally believed that the benefits of DR arise from eating fewer …

Increased longevity and improved health can be achieved in mammals by two feeding
regimens, caloric restriction (CR), which limits the amount of daily calorie intake, and …

The neuroendocrinology of ingestive behavior is a topic central to human health, particularly
in light of the prevalence of obesity, eating disorders, and diabetes. The study of food intake …

OBJECTIVE: Roux-en-Y gastric bypass (RYGB) produces rapid and dramatic weight loss in
very heavy obese patients. Up to 20% cannot sustain their weight loss beyond 2 to 3 y after …

Leptin is a hormone secreted by adipocytes that plays a pivotal role in regulation of food
intake, energy expenditure, and neuroendocrine function. Several lines of evidences …

One of the most profound hallmarks of mammalian hibernation is the dramatic reduction in
food intake during the winter months. Several species of hibernator completely cease food …