Cell invasion through extracellular matrix (ECM) has pivotal roles in cell dispersal during
development, immune cell trafficking, and cancer metastasis. Many elegant studies have …

Cachexia, a wasting syndrome that is often associated with cancer, is one of the primary
causes of death in cancer patients. Cancer cachexia occurs largely due to systemic …

Obesity significantly increases the risk of developing neurodegenerative disorders, yet the
precise mechanisms underlying this connection remain unclear. Defects in glial phagocytic …

Cancer cells constantly reprogram their metabolism as the disease progresses. However,
our understanding of the metabolic complexity of cancer remains incomplete. Extensive …

Extracellular signal-regulated kinase (ERK) lies downstream of a core signalling cascade
that controls all aspects of development and adult homeostasis. Recent developments have …

Glial cells are essential for the proper development and functioning of the peripheral
nervous system (PNS). The ability to study the biology of glial cells is therefore critical for our …

The mitochondrial electron transport chain (ETC) enables essential metabolic reactions;
nonetheless, the cellular responses to defects in mitochondria and the modulation of …

The structure and chemistry of metal–organic frameworks or MOFs dictate their properties
and functionalities. However, their architecture and form are essential for facilitating the …

Neural stem cells (NSCs) in the developing and adult brain undergo many different
transitions, tightly regulated by extrinsic and intrinsic factors. While the role of signalling …

In multicellular organisms, metabolic coordination across multiple tissues and cell types is
essential to satisfy regionalized energetic requirements and respond coherently to changing …