Dietary intake of caffeine has significantly increased in recent years, and beneficial and
harmful effects of caffeine have been extensively studied. This paper reviews antioxidant …

In addition to synthetic and semisynthetic compounds, natural products have received much
attention as prolific sources of lead compounds with therapeutic effects on various diseases …

Oocyte quality is essential for reproductive capacity, but it rapidly declines with age. In
addition to aging, maternal nutrition is a major concern in maintaining oocyte quality …

Abstract Epigallocatechin-3-gallate (EGCG) and caffeine, two phytochemicals found in a
wide range of natural dietary sources, have been reported to have protective effects against …

Caffeine, a methylxanthine derived from plants, is the most widely consumed ingredient in
daily life. Therefore, it is necessary to investigate the effects of caffeine intake on essential …

Caffeine intake is strongly linked to lipid metabolism. We previously reported the age-
dependent physiological effects of caffeine intake in a Caenorhabditis elegans model. Since …

The von Willebrand factor type D (VWD) domain in vitellogenin has recently been found to
bind tetrodotoxin. The way in which this protein domain associates with tetrodotoxin and …

Caffeine (1, 3, 7-trimethylxanthine) is a widely consumed bioactive substance worldwide.
Our recent study showed that a reduction in both reproduction and yolk protein production …

Vitamin B12 is an essential cofactor involved in the function of two enzymes: cytosolic
methionine synthase and mitochondrial methylmalonic-CoA mutase. In our previous studies …

Caffeine, a widely consumed stimulant, is known for its effects on alertness and fatigue
reduction by blockade of adenosine receptors. While it holds therapeutic potential, its …