The neurobiology of zinc in health and disease

CJ Frederickson, JY Koh, AI Bush - Nature Reviews Neuroscience, 2005 - nature.com
The use of zinc in medicinal skin cream was mentioned in Egyptian papyri from 2000 BC (for
example, the Smith Papyrus), and zinc has apparently been used fairly steadily throughout …

Molecular structure and function of the glycine receptor chloride channel

JW Lynch - Physiological reviews, 2004 - journals.physiology.org
The glycine receptor chloride channel (GlyR) is a member of the nicotinic acetylcholine
receptor family of ligand-gated ion channels. Functional receptors of this family comprise five …

Organization, control and function of extrasynaptic NMDA receptors

T Papouin, SHR Oliet - … of the Royal Society B: Biological …, 2014 - royalsocietypublishing.org
N-methyl d-aspartate receptors (NMDARs) exist in different forms owing to multiple
combinations of subunits that can assemble into a functional receptor. In addition, they are …

[HTML][HTML] The β subunit determines the ligand binding properties of synaptic glycine receptors

J Grudzinska, R Schemm, S Haeger, A Nicke… - Neuron, 2005 - cell.com
Inhibitory glycine receptors (GlyRs) regulate motor coordination and sensory signal
processing in spinal cord and other brain regions. GlyRs are pentameric proteins composed …

[HTML][HTML] Fireworks in the primate retina: in vitro photodynamics reveals diverse LGN-projecting ganglion cell types

DM Dacey, BB Peterson, FR Robinson, PD Gamlin - Neuron, 2003 - cell.com
Diverse cell types and parallel pathways are characteristic of the vertebrate nervous system,
yet it remains a challenge to define the basic components of most neural structures. We …

Effects of high-fat diet on insulin receptor function in rat hippocampus and the level of neuronal corticosterone

W Pratchayasakul, S Kerdphoo, P Petsophonsakul… - Life sciences, 2011 - Elsevier
AIM: Chronic consumption of a high-fat (HF) diet contributes to peripheral insulin resistance
and elevated plasma corticosterone. However, the effect of HF consumption on the …

[HTML][HTML] L-serine, an endogenous amino acid, is a potential neuroprotective agent for neurological disease and injury

L Ye, Y Sun, Z Jiang, G Wang - Frontiers in Molecular Neuroscience, 2021 - frontiersin.org
Central nervous system (CNS) lesions are major causes of human death and disability
worldwide, and they cause different extents of motor and sensory dysfunction in patients …

Gephyrin is critical for glycine receptor clustering but not for the formation of functional GABAergic synapses in hippocampal neurons

S Lévi, SM Logan, KR Tovar… - Journal of Neuroscience, 2004 - Soc Neuroscience
The role of the scaffolding protein gephyrin at hippocampal inhibitory synapses is not well
understood. A previous study reported a complete loss of synaptic clusters of the major …

The dynamics of GABA signaling: revelations from the circadian pacemaker in the suprachiasmatic nucleus

HE Albers, JC Walton, KL Gamble, JK McNeill IV… - Frontiers in …, 2017 - Elsevier
Virtually every neuron within the suprachiasmatic nucleus (SCN) communicates via
GABAergic signaling. The extracellular levels of GABA within the SCN are determined by a …

FGF21 improves cognition by restored synaptic plasticity, dendritic spine density, brain mitochondrial function and cell apoptosis in obese-insulin resistant male rats

P Sa-Nguanmoo, P Tanajak, S Kerdphoo… - Hormones and …, 2016 - Elsevier
Abstract Fibroblast growth factor 21 (FGF21) is an endocrine hormone which exerts
beneficial effects on metabolic regulation in obese and diabetic models. However, the effect …