Macrophage-targeted nanomedicine for the diagnosis and treatment of atherosclerosis

W Chen, M Schilperoort, Y Cao, J Shi, I Tabas… - Nature Reviews …, 2022 - nature.com
Nanotechnology could improve our understanding of the pathophysiology of atherosclerosis
and contribute to the development of novel diagnostic and therapeutic strategies to further …

Chemically engineered mesoporous silica nanoparticles-based intelligent delivery systems for theranostic applications in multiple cancerous/non-cancerous diseases

S Zhou, Q Zhong, Y Wang, P Hu, W Zhong… - Coordination Chemistry …, 2022 - Elsevier
In recent years, the unprecedented advances of biomedical nanotechnology have spurred
the development of drug delivery systems (DDSs) based on multifarious nanomaterials in …

Nanoparticle-based medicines: a review of FDA-approved materials and clinical trials to date

D Bobo, KJ Robinson, J Islam, KJ Thurecht… - Pharmaceutical …, 2016 - Springer
In this review we provide an up to date snapshot of nanomedicines either currently approved
by the US FDA, or in the FDA clinical trials process. We define nanomedicines as …

Gold nanoparticle‐mediated photothermal therapy: applications and opportunities for multimodal cancer treatment

RS Riley, ES Day - Wiley Interdisciplinary Reviews …, 2017 - Wiley Online Library
Photothermal therapy (PTT), in which nanoparticles embedded within tumors generate heat
in response to exogenously applied laser light, has been well documented as an …

Recent advances in nanomaterials for therapy and diagnosis for atherosclerosis

J Chen, X Zhang, R Millican, J Sherwood… - Advanced drug delivery …, 2021 - Elsevier
Atherosclerosis is a chronic inflammatory disease driven by lipid accumulation in arteries,
leading to narrowing and thrombosis. It affects the heart, brain, and peripheral vessels and is …

Silica–gold nanoparticles for atheroprotective management of plaques: results of the NANOM-FIM trial

AN Kharlamov, AE Tyurnina, VS Veselova, OP Kovtun… - Nanoscale, 2015 - pubs.rsc.org
Background: Atheroregression becomes an attractive target for cardiovascular treatment.
Some clinical trials have demonstrated that intensive therapy with rosuvastatin or …

Size, shape and surface chemistry of nano-gold dictate its cellular interactions, uptake and toxicity

C Carnovale, G Bryant, R Shukla, V Bansal - Progress in Materials Science, 2016 - Elsevier
Colloidal gold is undoubtedly one of the most extensively studied nanomaterials, with 1000s
of different protocols currently available to synthesise gold nanoparticles (AuNPs). While …

Leveraging physiology for precision drug delivery

W Sun, Q Hu, W Ji, G Wright, Z Gu - Physiological reviews, 2017 - journals.physiology.org
Physiological characteristics of diseases bring about both challenges and opportunities for
targeted drug delivery. Various drug delivery platforms have been devised ranging from …

Applications of inorganic nanoparticles in the diagnosis and therapy of atherosclerosis

T Dai, W He, C Yao, X Ma, W Ren, Y Mai, A Wu - Biomaterials science, 2020 - pubs.rsc.org
Atherosclerosis is a chronic progressive disease, which may result in serious clinical
outcomes, such as acute heart events or stroke with high mortality. At present, the clinical …

Nanopharmaceuticals (part 2): products in the pipeline

V Weissig, D Guzman-Villanueva - International journal of …, 2015 - Taylor & Francis
In part I of this review we assessed nanoscience-related definitions as applied to
pharmaceuticals and we discussed all 43 currently approved drug formulations, which are …