Beyond pore formation: Reorganization of the plasma membrane induced by pore-forming proteins

M Kulma, G Anderluh - Cellular and Molecular Life Sciences, 2021 - Springer
Pore-forming proteins (PFPs) are a heterogeneous group of proteins that are expressed and
secreted by a wide range of organisms. PFPs are produced as soluble monomers that bind …

Active tension and membrane friction mediate cortical flows and blebbing in a model actomyosin cortex

R Sakamoto, MP Murrell - Physical Review Research, 2024 - APS
Blebs, spherical membrane bulges of the cell membrane, are ubiquitous structures observed
in various biological phenomena, including apoptosis, cell division, to bleb-based cell …

Effect of electroporation and recovery medium pH on cell membrane permeabilization, cell survival and gene transfer efficiency in vitro

T Potočnik, D Miklavčič, AM Lebar - Bioelectrochemistry, 2019 - Elsevier
Electroporation is a method which uses an adequate number of electric pulses of enough
amplitude, duration and number applied to cells, thus inducing transient permeabilization of …

Force-mediated cellular anisotropy and plasticity dictate the elongation dynamics of embryos

C Fang, X Wei, X Shao, Y Lin - Science Advances, 2021 - science.org
We developed a unified dynamic model to explain how cellular anisotropy and plasticity,
induced by alignment and severing/rebundling of actin filaments, dictate the elongation …

Monitoring the response of a model protocell to dye and surfactant molecules through second harmonic generation and fluorescence imaging

B Li, J Li, S Chen, Q Yuan, C Fang… - Physical Chemistry …, 2024 - pubs.rsc.org
Probing the interaction between molecules and protocells is crucial for understanding the
passive transport of functional molecules in and out of artificial and real cells. Second …

Interaction of an Oomycete Nep1-like Cytolysin with Natural and Plant Cell-Mimicking Membranes

T Snoj, T Lukan, K Gruden, G Anderluh - The Journal of Membrane Biology, 2024 - Springer
Plants are attacked by various pathogens that secrete a variety of effectors to damage host
cells and facilitate infection. One of the largest and so far understudied microbial protein …

Cellular blebs and membrane invaginations are coupled through membrane tension buffering

I Lavi, M Goudarzi, E Raz, NS Gov, R Voituriez… - Biophysical Journal, 2019 - cell.com
Bleb-type cellular protrusions play key roles in a range of biological processes. It was
recently found that bleb growth is facilitated by a local supply of membrane from tubular …

Modelling membrane curvature generation using mechanics and machine learning

SA Malingen, P Rangamani - Journal of the Royal …, 2022 - royalsocietypublishing.org
The deformation of cellular membranes regulates trafficking processes, such as exocytosis
and endocytosis. Classically, the Helfrich continuum model is used to characterize the forces …

3D computational modeling of bleb initiation dynamics

W Strychalski - Frontiers in Physics, 2021 - frontiersin.org
Blebbing occurs in cells under high cortical tension when the membrane locally detaches
from the actin cortex, resulting in pressure-driven flow of the cytosol and membrane …

[HTML][HTML] Scanning electron microscopy analysis of synovial and adipose mesenchymal stem cells adhering to cartilage

Y Fuchioka, K Endo, Y Sakamaki, T Tanimoto… - Regenerative …, 2024 - Elsevier
Abstract Introduction Mesenchymal stem cells (MSCs) are increasingly used for intra-
articular injections in the treatment of knee osteoarthritis. The aim of this study was to use …