Physical plasmas generate unique mixes of reactive oxygen and nitrogen species (RONS or
ROS). Only a bit more than a decade ago, these plasmas, operating at body temperature …

Selenium is a vital trace element present as selenocysteine (Sec) in proteins that are, thus,
known as selenoproteins. Humans have 25 selenoproteins, most of which are functionally …

Eukaryotic mitochondria resulted from symbiotic incorporation of α-proteobacteria into
ancient archaea species. During evolution, mitochondria lost most of the prokaryotic …

The thioredoxin (Trx) system comprises Trx, truncated Trx (Trx-80), Trx reductase, and
NADPH, besides a natural Trx inhibitor, the thioredoxin-interacting protein (TXNIP). This …

Arsenic trioxide (ATO) is an effective cancer therapeutic drug for acute promyelocytic
leukemia and has potential anticancer activity against a wide range of solid tumors. ATO …

Abstract 2852 The polyphenolic phytoalexin resveratrol (RSV) and its analogues have
received tremendous attention over the past couple of decades because of a number of …

Thioredoxin reductase 1 (TrxR1) in cytosol is the only known reductant of oxidized
thioredoxin 1 (Trx1) in vivo so far. We and others found that aurothioglucose (ATG), a well …

Reactive oxygen species (ROS) are not only cytotoxic products from external and internal
environment, but also important mediators of redox signaling. Therefore, thioredoxin (Trx) as …

Significance: Thioredoxin (Trx) and thioredoxin reductase are two core members of the Trx
system. The system bridges the gap between the universal reducing equivalent NADPH and …

Fucoxanthin, a natural biologically active substance isolated from Ishige okamurae,
evidences antitumor activity in human leukemia cell HL-60 cells via the induction of …