[HTML][HTML] The PE-PPE family of Mycobacterium tuberculosis: proteins in disguise
C D'Souza, U Kishore, AG Tsolaki - Immunobiology, 2023 - Elsevier
Mycobacterium tuberculosis has thrived in parallel with humans for millennia, and despite
our efforts, M. tuberculosis continues to plague us, currently infecting a third of the world's …
our efforts, M. tuberculosis continues to plague us, currently infecting a third of the world's …
[HTML][HTML] The Mycobacterium tuberculosis PE_PGRS Protein Family Acts as an Immunological Decoy to Subvert Host Immune Response
Mycobacterium tuberculosis (M. tb) is a successful pathogen that can reside within the
alveolar macrophages of the host and can survive in a latent stage. The pathogen has …
alveolar macrophages of the host and can survive in a latent stage. The pathogen has …
[HTML][HTML] Role of C-terminal domain of Mycobacterium tuberculosis PE6 (Rv0335c) protein in host mitochondrial stress and macrophage apoptosis
PE/PPE proteins of Mycobacterium tuberculosis (Mtb) target the host organelles to dictate
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
the outcome of infection. This study investigated the significance of PE6/Rv0335c protein's …
PE_PGRS45 (Rv2615c) protein of Mycobacterium tuberculosis perturbs mitochondria of macrophages
The PE_PGRS proteins have coevolved with the antigenic ESX‐V secretory system and are
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …
abundant in pathogenic Mycobacterium. Only a few PE_PGRS proteins have been …
Mycobacterium tuberculosis dormancy regulon proteins Rv2627c and Rv2628 as Toll like receptor agonist and as potential adjuvant
During latency, DosR proteins of Mycobacterium tuberculosis (M. tb) get activated and help
the bacterium to remain dormant. We have shown earlier that 2 such proteins Rv2627c and …
the bacterium to remain dormant. We have shown earlier that 2 such proteins Rv2627c and …
[HTML][HTML] The Mycobacterium tuberculosis PE15/PPE20 complex transports calcium across the outer membrane
The mechanisms by which nutrients traverse the Mycobacterium tuberculosis (Mtb) outer
membrane remain mostly unknown and, in the absence of classical porins, likely involve …
membrane remain mostly unknown and, in the absence of classical porins, likely involve …
Expression of a unique M. tuberculosis DNA MTase Rv1509 in M. smegmatis alters the gene expression pattern and enhances virulence
P Manjunath, J Ahmad, J Samal, A Rani… - Frontiers in …, 2024 - frontiersin.org
Mycobacterium tuberculosis (M. tb) genome encompasses 4,173 genes, about a quarter of
which remain uncharacterized and hypothetical. Considering the current limitations …
which remain uncharacterized and hypothetical. Considering the current limitations …
Recognition of Mycobacterium tuberculosis by macrophage Toll-like receptor and its role in autophagy
L Wei, L Liu, Z Meng, K Qi, X Gao, J Feng, J Luo - Inflammation Research, 2024 - Springer
Background The pathogen responsible for tuberculosis is called Mycobacterium
tuberculosis. Its interaction with macrophages has a significant impact on the onset and …
tuberculosis. Its interaction with macrophages has a significant impact on the onset and …
[HTML][HTML] Cellular and molecular mechanisms in mycobacterial infection
NE Nieuwenhuizen, JC Evans - International Journal of Molecular …, 2022 - mdpi.com
Tuberculosis (TB), caused by the bacillus Mycobacterium tuberculosis (Mtb), remains a
leading cause of death by infectious disease, overshadowed only recently by the COVID-19 …
leading cause of death by infectious disease, overshadowed only recently by the COVID-19 …