Non-viral COVID-19 vaccine delivery systems

KS Park, X Sun, ME Aikins, JJ Moon - Advanced drug delivery reviews, 2021 - Elsevier
The novel corona virus termed severe acute respiratory syndrome coronavirus 2 (SARS-
CoV-2) has spread throughout the globe at a formidable speed, causing tens of millions of …

[HTML][HTML] Advanced nanocarrier-and microneedle-based transdermal drug delivery strategies for skin diseases treatment

F Qu, R Geng, Y Liu, J Zhu - Theranostics, 2022 - ncbi.nlm.nih.gov
Skin diseases are the fourth leading cause of nonfatal and chronic skin diseases, acting as a
global burden and affecting the world economy. Skin diseases severely impact the patients' …

[HTML][HTML] Stimuli-responsive transdermal microneedle patches

P Makvandi, R Jamaledin, G Chen… - Materials Today, 2021 - Elsevier
Microneedle (MN) patches consisting of miniature needles have emerged as a promising
tool to perforate the stratum corneum and translocate biomolecules into the dermis in a …

Microneedle array systems for long-acting drug delivery

LK Vora, K Moffatt, IA Tekko, AJ Paredes… - European Journal of …, 2021 - Elsevier
The development of microneedles (MNs) assisted drug delivery technologies have been
highly active for more than two decades. The minimally invasive and self-administered MN …

Microneedles for painless transdermal immunotherapeutic applications

H Amani, MA Shahbazi, C D'Amico, F Fontana… - Journal of Controlled …, 2021 - Elsevier
Immunotherapy has recently garnered plenty of attention to improve the clinical outcomes in
the treatment of various diseases. However, owing to the dynamic nature of the immune …

Responsive biomaterials: optimizing control of cancer immunotherapy

L Xue, AS Thatte, D Mai, RM Haley, N Gong… - Nature Reviews …, 2024 - nature.com
Immunotherapy has emerged as an eminent and effective modality in the treatment of
cancer. However, current cancer immunotherapies lack spatial and temporal control …

In Situ Transforming RNA Nanovaccines from Polyethylenimine Functionalized Graphene Oxide Hydrogel for Durable Cancer Immunotherapy

Y Yin, X Li, H Ma, J Zhang, D Yu, R Zhao, S Yu… - Nano Letters, 2021 - ACS Publications
Messenger RNA (mRNA) vaccine is a promising candidate in cancer immunotherapy as it
can encode tumor-associated antigens with an excellent safety profile. Unfortunately, the …

Microneedle-mediated vaccination: innovation and translation

T Sheng, B Luo, W Zhang, X Ge, J Yu, Y Zhang… - Advanced drug delivery …, 2021 - Elsevier
Vaccine administration by subcutaneous or intramuscular injection is the most commonly
prescribed route for inoculation, however, it is often associated with some deficiencies such …

Separable microneedle patch to protect and deliver DNA nanovaccines against COVID-19

Y Yin, W Su, J Zhang, W Huang, X Li, H Ma, M Tan… - ACS …, 2021 - ACS Publications
The successful control of coronavirus disease 2019 (COVID-19) pandemic is not only relying
on the development of vaccines, but also depending on the storage, transportation, and …

Nanoparticles in tumor microenvironment remodeling and cancer immunotherapy

Q Lu, D Kou, S Lou, M Ashrafizadeh, AR Aref… - Journal of Hematology & …, 2024 - Springer
Cancer immunotherapy and vaccine development have significantly improved the fight
against cancers. Despite these advancements, challenges remain, particularly in the clinical …