Gastric peristalsis is critically dependent on an underlying electrical conduction system.
Recent years have witnessed substantial progress in clarifying the operations of this system …

Gastric arrhythmia continues to be of uncertain diagnostic and therapeutic significance.
However, recent progress has been substantial, with technical advances, theoretical insights …

Emergent research in the past decades has brought to light the importance of lymphatic
vessels in tissue homeostasis, immunity, metabolism, and inflammation. In Nature, Klotz et …

Over the last two decades, high-resolution (HR) mapping has emerged as a powerful
technique to study normal and abnormal bioelectrical events in the gastrointestinal (GI) tract …

Gastric pacing has shown preclinical success in modulating bioelectrical slow-wave activity
and has potential as a novel therapy for functional motility disorders. However, the …

Key points• Extracellular recording techniques are commonly used to measure bioelectrical
activity. However, the validity of gastrointestinal extracellular recordings has recently been …

Gastrointestinal (GI) motility is regulated in part by electrophysiological events called slow
waves, which are generated by the interstitial cells of Cajal (ICC). Slow waves propagate by …

A key discovery in gastrointestinal motility has been the central role played by interstitial
cells of Cajal (ICC) in generating electrical slow waves that coordinate contractions …

Disruptions in the orderly activation and recovery of electrical excitation traveling through the
heart and the gastrointestinal (GI) tract can lead to arrhythmogenesis. For example, cardiac …

The small intestine is a convoluted flexible tube of inconstant form and capacity through
which chyme is propelled and mixed by varying patterns of contraction. These inconstancies …