Biomimetic and mechanically supportive 3D printed scaffolds for cartilage and osteochondral tissue engineering using photopolymers and digital light processing
SA Schoonraad, KM Fischenich, KN Eckstein… - …, 2021 - iopscience.iop.org
Successful 3D scaffold designs for musculoskeletal tissue engineering necessitate full
consideration of the form and function of the tissues of interest. When designing structures …
consideration of the form and function of the tissues of interest. When designing structures …
A review of methods to study hydration effects on cartilage friction
AC Moore, JL Schrader, JJ Ulvila… - … -Materials, Surfaces & …, 2017 - Taylor & Francis
The mechanical and tribological responses of cartilage depend strongly on its hydration
state, which is a function of the mechanical and tribological conditions of the contact. The …
state, which is a function of the mechanical and tribological conditions of the contact. The …
Poroelasticity-driven lubrication in hydrogel interfaces
ER Reale, AC Dunn - Soft matter, 2017 - pubs.rsc.org
It is widely accepted that hydrogel surfaces are slippery, and have low friction, but dynamic
applied stresses alter the hydrogel composition at the interface as water is displaced. The …
applied stresses alter the hydrogel composition at the interface as water is displaced. The …
Indentation mapping revealed poroelastic, but not viscoelastic, properties spanning native zonal articular cartilage
Osteoarthrosis is a debilitating disease affecting millions, yet engineering materials for
cartilage regeneration has proven difficult because of the complex microstructure of this …
cartilage regeneration has proven difficult because of the complex microstructure of this …
Load-induced fluid pressurisation in hydrogel systems before and after reinforcement by melt-electrowritten fibrous meshes
Fluid pressure develops transiently within mechanically-loaded, cell-embedding hydrogels,
but its magnitude depends on the intrinsic material properties of the hydrogel and cannot be …
but its magnitude depends on the intrinsic material properties of the hydrogel and cannot be …
Cartilage and joint lubrication: new insights into the role of hydrodynamics
Cartilage is slippery when hydrated but it loses hydration and lubricity during loading.
However, dehydrated cartilage regains lubricity during high-speed sliding in the stationary …
However, dehydrated cartilage regains lubricity during high-speed sliding in the stationary …
Comparative tribology II–Measurable biphasic tissue properties have predictable impacts on cartilage rehydration and lubricity
Healthy articular cartilage supports load bearing and frictional properties unmatched among
biological tissues and man-made bearing materials. Balancing fluid exudation and recovery …
biological tissues and man-made bearing materials. Balancing fluid exudation and recovery …
Quantifying cartilage contact modulus, tension modulus, and permeability with Hertzian biphasic creep
This paper describes a new method, based on a recent analytical model (Hertzian biphasic
theory (HBT)), to simultaneously quantify cartilage contact modulus, tension modulus, and …
theory (HBT)), to simultaneously quantify cartilage contact modulus, tension modulus, and …
A 3D printed mimetic composite for the treatment of growth plate injuries in a rabbit model
Y Yu, KM Fischenich, SA Schoonraad… - npj Regenerative …, 2022 - nature.com
Growth plate injuries affecting the pediatric population may cause unwanted bony repair
tissue that leads to abnormal bone elongation. Clinical treatment involves bony bar …
tissue that leads to abnormal bone elongation. Clinical treatment involves bony bar …
Core–shell patterning of synthetic hydrogels via interfacial bioorthogonal chemistry for spatial control of stem cell behavior
A new technique is described for the patterning of cell-guidance cues in synthetic
extracellular matrices (ECM) for tissue engineering applications. Using s-tetrazine modified …
extracellular matrices (ECM) for tissue engineering applications. Using s-tetrazine modified …