[HTML][HTML] Silencing neurons: tools, applications, and experimental constraints
Reversible silencing of neuronal activity is a powerful approach for isolating the roles of
specific neuronal populations in circuit dynamics and behavior. In contrast with neuronal …
specific neuronal populations in circuit dynamics and behavior. In contrast with neuronal …
Microbial rhodopsins: diversity, mechanisms, and optogenetic applications
EG Govorunova, OA Sineshchekov, H Li… - Annual review of …, 2017 - annualreviews.org
Microbial rhodopsins are a family of photoactive retinylidene proteins widespread
throughout the microbial world. They are notable for their diversity of function, using …
throughout the microbial world. They are notable for their diversity of function, using …
Dynamics and mechanism of a light-driven chloride pump
Chloride transport by microbial rhodopsins is an essential process for which molecular
details such as the mechanisms that convert light energy to drive ion pumping and ensure …
details such as the mechanisms that convert light energy to drive ion pumping and ensure …
[HTML][HTML] Femtosecond-to-millisecond structural changes in a light-driven sodium pump
Light-driven sodium pumps actively transport small cations across cellular membranes.
These pumps are used by microorganisms to convert light into membrane potential and …
These pumps are used by microorganisms to convert light into membrane potential and …
Structural insights into ion conduction by channelrhodopsin 2
O Volkov, K Kovalev, V Polovinkin, V Borshchevskiy… - Science, 2017 - science.org
INTRODUCTION Ion channels are integral membrane proteins that upon stimulation
modulate the flow of ions across the cell or organelle membrane. The resulting electrical …
modulate the flow of ions across the cell or organelle membrane. The resulting electrical …
[HTML][HTML] Salinity tolerance in plants. Quantitative approach to ion transport starting from halophytes and stepping to genetic and protein engineering for manipulating …
V Volkov - Frontiers in Plant Science, 2015 - frontiersin.org
Ion transport is the fundamental factor determining salinity tolerance in plants. The Review
starts from differences in ion transport between salt tolerant halophytes and salt-sensitive …
starts from differences in ion transport between salt tolerant halophytes and salt-sensitive …
[HTML][HTML] Molecular mechanism of light-driven sodium pumping
The light-driven sodium-pumping rhodopsin KR2 from Krokinobacter eikastus is the only
non-proton cation active transporter with demonstrated potential for optogenetics. However …
non-proton cation active transporter with demonstrated potential for optogenetics. However …
Inward H+ pump xenorhodopsin: Mechanism and alternative optogenetic approach
Generation of an electrochemical proton gradient is the first step of cell bioenergetics. In
prokaryotes, the gradient is created by outward membrane protein proton pumps. Inward …
prokaryotes, the gradient is created by outward membrane protein proton pumps. Inward …
Mechanism of transmembrane signaling by sensor histidine kinases
INTRODUCTION Microorganisms obtain most of the information about their environments
through membrane-associated signaling systems. One of the most abundant classes of …
through membrane-associated signaling systems. One of the most abundant classes of …
Structure and mechanisms of sodium-pumping KR2 rhodopsin
Rhodopsins are the most universal biological light-energy transducers and abundant
phototrophic mechanisms that evolved on Earth and have a remarkable diversity and …
phototrophic mechanisms that evolved on Earth and have a remarkable diversity and …