The regulation of DNA supercoiling across evolution
A Duprey, EA Groisman - Protein Science, 2021 - Wiley Online Library
DNA supercoiling controls a variety of cellular processes, including transcription,
recombination, chromosome replication, and segregation, across all domains of life. As a …
recombination, chromosome replication, and segregation, across all domains of life. As a …
[HTML][HTML] Expression, Regulation, and Function of β-Defensins in the Bovine Mammary Glands: Current Knowledge and Future Perspectives
Simple Summary Mastitis, a common ailment affecting dairy cows, carries significant
economic implications. Common treatments with synthetic antimicrobials face challenges …
economic implications. Common treatments with synthetic antimicrobials face challenges …
Ang II promotes ET-1 production by regulating NOX2 activity through transcription factor Oct-1
J Kamhieh-Milz, L Chen, C Goettsch… - … and Vascular Biology, 2023 - Am Heart Assoc
BACKGROUND: Increasing evidence suggests that superoxide ions produced by NOX
(nicotinamide adenine dinucleotide phosphate oxidases) mediate vascular effects of Ang II …
(nicotinamide adenine dinucleotide phosphate oxidases) mediate vascular effects of Ang II …
[HTML][HTML] Patients experiencing statin-induced myalgia exhibit a unique program of skeletal muscle gene expression following statin re-challenge
MB Elam, G Majumdar, K Mozhui, IC Gerling, SR Vera… - PLoS …, 2017 - journals.plos.org
Statins, the 3-hydroxy-3-methyl-glutaryl (HMG)-CoA reductase inhibitors, are widely
prescribed for treatment of hypercholesterolemia. Although statins are generally well …
prescribed for treatment of hypercholesterolemia. Although statins are generally well …
[HTML][HTML] HLA-C level is regulated by a polymorphic Oct1 binding site in the HLA-C promoter region
Differential HLA-C levels influence several human diseases, but the mechanisms
responsible are incompletely characterized. Using a validated prediction algorithm, we …
responsible are incompletely characterized. Using a validated prediction algorithm, we …
Methyl CpG level at distal part of heat‐shock protein promoter HSP70 exhibits epigenetic memory for heat stress by modulating recruitment of POU2F1‐associated …
T Kisliouk, T Cramer, N Meiri - Journal of neurochemistry, 2017 - Wiley Online Library
Depending on its stringency, exposure to heat in early life leads to either resilience or
vulnerability to heat stress later in life. We hypothesized that epigenetic alterations in genes …
vulnerability to heat stress later in life. We hypothesized that epigenetic alterations in genes …
Hypomethylation of the IL8 promoter in nasal epithelial cells of patients with chronic rhinosinusitis with nasal polyps
J Li, J Jiao, M Wang, Y Gao, Y Li, Y Wang… - Journal of Allergy and …, 2019 - Elsevier
Background IL-8 is an important chemokine implicated in the pathogenesis of chronic
rhinosinusitis (CRS), but little is known about epigenetic regulation of IL8 in the …
rhinosinusitis (CRS), but little is known about epigenetic regulation of IL8 in the …
[HTML][HTML] Gene networks and transcriptional regulators associated with liver cancer development and progression
T Meier, M Timm, M Montani, L Wilkens - BMC Medical Genomics, 2021 - Springer
Background Treatment options for hepatocellular carcinoma (HCC) are limited, and overall
survival is poor. Despite the high frequency of this malignoma, its basic disease …
survival is poor. Despite the high frequency of this malignoma, its basic disease …
Epigenetics of CD4+ T cells in autoimmune diseases
Z Wang, C Chang, Q Lu - Current opinion in rheumatology, 2017 - journals.lww.com
In this review, we decipher findings that identify how epigenetic regulates CD4+ T-cell
functions and the advancement of novel epigenetic mechanisms in systemic lupus …
functions and the advancement of novel epigenetic mechanisms in systemic lupus …
[HTML][HTML] Diversity of human and mouse homeobox gene expression in development and adult tissues
TL Dunwell, PWH Holland - BMC developmental biology, 2016 - Springer
Background Homeobox genes encode a diverse set of transcription factors implicated in a
vast range of biological processes including, but not limited to, embryonic cell fate …
vast range of biological processes including, but not limited to, embryonic cell fate …