Natural products to prevent drug resistance in cancer chemotherapy: a review

R Yuan, Y Hou, W Sun, J Yu, X Liu… - Annals of the new …, 2017 - Wiley Online Library
Chemotherapy is the standard internal medical treatment for cancer. However, the
resistance of cancer cells to nearly all kinds of chemotherapeutic drugs and targeted drugs …

Hypericin and its anticancer effects: From mechanism of action to potential therapeutic application

N Choudhary, TE Collignon, D Tewari, A Bishayee - Phytomedicine, 2022 - Elsevier
Background Emerging studies indicate that hypericin has diverse pharmacological actions
and exhibits potential for treatment of various types of cancer. Purpose The current review …

Glycyrrhizic acid: A promising carrier material for anticancer therapy

X Su, L Wu, M Hu, W Dong, M Xu, P Zhang - Biomedicine & …, 2017 - Elsevier
Drug delivery systems have become an integral part of anticancer drugs today. Design of
novel drug carriers may lead to significant enhancement in antineoplastic therapy …

A multiple-targets alkaloid nuciferine overcomes paclitaxel-induced drug resistance in vitro and in vivo

RM Liu, P Xu, Q Chen, S Feng, Y Xie - Phytomedicine, 2020 - Elsevier
Objective Multidrug resistance (MDR) is the major barrier to the successful treatment of
chemotherapy. Compounds from nature products working as MDR sensitizers provided new …

Curcumin inhibits urothelial tumor development by suppressing IGF2 and IGF2-mediated PI3K/AKT/mTOR signaling pathway

B Tian, Y Zhao, T Liang, X Ye, Z Li, D Yan… - Journal of drug …, 2017 - Taylor & Francis
We have previously reported that curcumin inhibits urothelial tumor development in a rat
bladder carcinogenesis model. In this study, we report that curcumin inhibits urothelial tumor …

Marine mollusk‐derived agents with antiproliferative activity as promising anticancer agents to overcome chemotherapy resistance

ML Ciavatta, F Lefranc, M Carbone… - Medicinal Research …, 2017 - Wiley Online Library
The chemical investigation of marine mollusks has led to the isolation of a wide variety of
bioactive metabolites, which evolved in marine organisms as favorable adaptations to …

Schiff bases and their metal complexes to target and overcome (multidrug) resistance in cancer

A Podolski-Renić, AČ Gašparović, A Valente… - European Journal of …, 2024 - Elsevier
Overcoming multidrug resistance (MDR) is one of the major challenges in cancer therapy. In
this respect, Schiff base-related compounds (bearing a R 1 R 2 Cdouble bondNR 3 bond) …

[HTML][HTML] Lung cancer management with silibinin: a historical and translational perspective

S Verdura, E Cuyàs, V Ruiz-Torres, V Micol, J Joven… - Pharmaceuticals, 2021 - mdpi.com
The flavonolignan silibinin, the major bioactive component of the silymarin extract of Silybum
marianum (milk thistle) seeds, is gaining traction as a novel anti-cancer therapeutic. Here …

Anticancer properties of essential oils: an overview

MA Andrade, MA Braga, PHS Cesar… - Current cancer drug …, 2018 - ingentaconnect.com
Background: Essential oils are complex mixtures of low molecular weight compounds
extracted from plants. Their main constituents are terpenes and phenylpropanoids, which …

[HTML][HTML] Combination of shikonin with paclitaxel overcomes multidrug resistance in human ovarian carcinoma cells in a P-gp-independent manner through enhanced …

Z Wang, J Yin, M Li, J Shen, Z Xiao, Y Zhao, C Huang… - Chinese medicine, 2019 - Springer
Background Shikonin (SKN), a naphthoquinone compound, is isolated from Chinese herbal
medicine Lithospermum root and has been studied as an anticancer drug candidate in …