C–H functionalization has been emerging as a powerful method to establish carbon–carbon
and carbon–heteroatom bonds. Many efforts have been devoted to transition-metal …

In this contribution, we provide a comprehensive overview of C–H activation methods
promoted by NHC–transition metal complexes, covering the literature since 2002 (the year …

Often stoichiometric amounts of gold find use in materials science; occasionally gold is even
used as a support. This review discusses the contributions of gold catalysis, both …

Three-and four-membered rings, widespread motifs in nature and medicinal chemistry, have
fascinated chemists ever since their discovery. However, due to energetic considerations …

In 1994, Ye and McKervey published a paper in Chemical Reviews entitled “Organic
Synthesis with α-Diazocarbonyl Compounds”. 1 Our intention then was to draw attention to …

Abstract (Hetero) arenes continue to prove their indispensability in pharmaceuticals,
materials science, and synthetic chemistry. As such, the controllable modification of …

Gold carbenes are highly active intermediates in homogeneous gold catalysis, enabling a
large array of transformations such as C–H/X–H insertions, cyclopropanations, and 1, 2 …

Metal carbenes, generated from the decomposition of diazo compounds by transition-
metals, have a broad range of applications in organic synthesis. The progress of organic …

For the past dozen years, homogeneous gold catalysis has evolved from a little known topic
in organic synthesis to a fully blown research field of significant importance to synthetic …

This Feature Article presents and discusses the use of different methods to quantify and
explore the steric impact of N-heterocyclic carbene (NHC) ligands. These include (a) the …