The perception that intracellular lipolysis is a straightforward process that releases fatty
acids from fat stores in adipose tissue to generate energy has experienced major revisions …

The breakthrough discoveries of leptin and adiponectin more than two decades ago led to a
widespread recognition of adipose tissue as an endocrine organ. Many more adipose tissue …

Igniting thermogenesis within white adipose tissue (ie, promoting expression and activity of
the uncoupling protein UCP1) has attracted much interest. Numerous" browning agents" …

Our understanding of adipose tissue biology has progressed rapidly since the turn of the
century. White adipose tissue has emerged as a key determinant of healthy metabolism and …

So far, the connections between obesity and skeleton have been extensively explored, but
the results are inconsistent. Obesity is thought to affect bone health through a variety of …

Brown adipose tissue (BAT) is a unique tissue that is able to convert chemical energy
directly into heat when activated by the sympathetic nervous system. While initially believed …

Obesity is associated with severe metabolic diseases such as type 2 diabetes, insulin
resistance, cardiovascular disease and some forms of cancer. The pathophysiology of …

Perivascular adipose tissue (PVAT), the adipose tissue that surrounds most of the
vasculature, has emerged as an active component of the blood vessel wall regulating …

Brown and beige adipocytes arise from distinct developmental origins. Brown adipose tissue
(BAT) develops embryonically from precursors that also give to skeletal muscle. Beige fat …

Atherosclerosis, for which hyperlipidemia is a major risk factor, is the leading cause of
morbidity and mortality in Western society, and new therapeutic strategies are highly …