Doxorubicin induced cardio toxicity through sirtuins mediated mitochondrial disruption
N Ahmad, A Ullah, P Chu, W Tian, Z Tang… - Chemico-Biological …, 2022 - Elsevier
The chemotherapeutic drug Doxorubicin is the most commonly prescribed in the world.
However, its clinical wide application is limited due to harmful side effects like cardiotoxicity …
However, its clinical wide application is limited due to harmful side effects like cardiotoxicity …
[HTML][HTML] East wind, west wind: toward the modernization of traditional Chinese medicine
E Yagüe, H Sun, Y Hu - Frontiers in Neuroscience, 2022 - frontiersin.org
Traditional Chinese medicine (TCM) has used herbal remedies for more than 2,000 years.
The use of complimentary therapies has increased dramatically during the last years …
The use of complimentary therapies has increased dramatically during the last years …
Main active components of Si-Miao-Yong-An decoction (SMYAD) attenuate autophagy and apoptosis via the PDE5A-AKT and TLR4-NOX4 pathways in isoproterenol …
M Liao, Q Xie, Y Zhao, C Yang, C Lin, G Wang… - Pharmacological …, 2022 - Elsevier
Heart failure (HF), the main cause of death in patients with many cardiovascular diseases,
has been reported to be closely related to the complicated pathogenesis of autophagy …
has been reported to be closely related to the complicated pathogenesis of autophagy …
Novel pterostilbene derivatives ameliorate heart failure by reducing oxidative stress and inflammation through regulating Nrf2/NF-κB signaling pathway
X Yang, Z Liu, M Fang, T Zou, Z Zhang, X Meng… - European journal of …, 2023 - Elsevier
Pterostilbene is a demethylated resveratrol derivative with attractive anti-inflammatory, anti-
tumor and anti-oxidative stress activities. However, the clinical use of pterostilbene is limited …
tumor and anti-oxidative stress activities. However, the clinical use of pterostilbene is limited …
[HTML][HTML] Daucosterol Alleviates Alcohol− Induced Hepatic Injury and Inflammation through P38/NF− κB/NLRP3 Inflammasome Pathway
F Zhang, M Wang, Y Zha, J Zhou, J Han, S Zhang - Nutrients, 2023 - mdpi.com
Alcoholic liver disease (ALD) is caused by chronic excessive alcohol consumption, which
leads to inflammation, oxidative stress, lipid accumulation, liver fibrosis/cirrhosis, and even …
leads to inflammation, oxidative stress, lipid accumulation, liver fibrosis/cirrhosis, and even …
Apocynum venetum leaf extract alleviated doxorubicin-induced cardiotoxicity through the AKT/Bcl-2 signaling pathway
Background Doxorubicin (DOX) is a broad-spectrum anti-tumor drug that has been
associated with cardiotoxicity. Plant extracts have been shown to confer protection against …
associated with cardiotoxicity. Plant extracts have been shown to confer protection against …
[HTML][HTML] Daidzein alleviates doxorubicin-induced heart failure via the SIRT3/FOXO3a signaling pathway
H Li, M Zhang, Y Wang, K Gong, T Yan, D Wang… - Food & Function, 2022 - pubs.rsc.org
Heart failure (HF) is a clinical syndrome characterized by typical symptoms that usually
occur at the end stage of various heart diseases and lead to death. Daidzein (DAI), an …
occur at the end stage of various heart diseases and lead to death. Daidzein (DAI), an …
[HTML][HTML] Date palm pollen extract avert doxorubicin-induced cardiomyopathy fibrosis and associated oxidative/nitrosative stress, inflammatory cascade, and apoptosis …
Simple Summary The use of date palm pollen ethanolic extract (DPPE) is a conventional
approach in improving the side-effects induced by Doxorubicin (DOX). DPPE mitigated DOX …
approach in improving the side-effects induced by Doxorubicin (DOX). DPPE mitigated DOX …
[HTML][HTML] Total flavonoids of Selaginella tamariscina (P. Beauv.) Spring ameliorates doxorubicin-induced cardiotoxicity by modulating mitochondrial dysfunction and …
L Gao, P Yuan, Y Wei, Y Fu, Y Hou, P Li, Y Chen… - Phytomedicine, 2022 - Elsevier
Background Doxorubicin (DOX) is a highly effective chemotherapeutic that is effective for
various tumours. However, the clinical application of DOX has been limited by adverse …
various tumours. However, the clinical application of DOX has been limited by adverse …
Adiponectin agonist ADP355 ameliorates doxorubicin-induced cardiotoxicity by decreasing cardiomyocyte apoptosis and oxidative stress
D Zhao, C Xue, J Li, K Feng, P Zeng, Y Chen… - Biochemical and …, 2020 - Elsevier
Doxorubicin (DOX) is an anthracycline derivative and widely used as an anticancer drug.
However, the severe cardiotoxicity of DOX limits its application. ADP355 is an adiponectin …
However, the severe cardiotoxicity of DOX limits its application. ADP355 is an adiponectin …