The acronym ESKAPE includes six nosocomial pathogens that exhibit multidrug resistance
and virulence: Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae …

With the emerging threat of infections caused by multidrug resistant bacteria, phages have
been reconsidered as an alternative for treating infections caused by tenacious pathogens …

In contrast to planktonic cells, bacteria imbedded biofilms are notoriously refractory to
treatment by antibiotics or bacteriophage (phage) used alone. Given that the mechanisms of …

Bacteriophages are bacterial viruses that infect the host after successful receptor recognition
and adsorption to the cell surface. The irreversible adherence followed by genome material …

Emergence of antibiotic resistance presents a major setback to global health, and shortage
of antibiotic pipelines has created an urgent need for development of alternative therapeutic …

Species in the genus Pseudomonas thrive in a diverse set of ecological niches and include
crucial pathogens, such as the human pathogen Pseudomonas aeruginosa and the plant …

With an increase in cases of multidrug-resistant Pseudomonas aeruginosa, alternative and
adjunct treatments are needed, leading to renewed interest in bacteriophage therapy. There …

We recently discovered that some bacteriophages establish a nucleus-like replication
compartment (phage nucleus), but the core genes that define nucleus-based phage …

Pseudomonas aeruginosa and Staphylococcus aureus are opportunistic pathogens and are
commonly found in polymicrobial biofilm-associated diseases, namely chronic wounds …

Phage therapy is drawing more interest as antibiotic resistance becomes an ever more
serious threat to public health. Bacterial biofilms represent a major obstacle in the fight …