Mitochondrial disorders are among the most frequent inborn errors of metabolism, their
primary cause being the dysfunction of the oxidative phosphorylation system (OXPHOS) …

Mitochondria are double‐membrane‐bound organelles that are present in all nucleated
eukaryotic cells and are responsible for the production of cellular energy in the form of ATP …

Complex I (NADH: ubiquinone oxidoreductase) is the first enzyme of the mitochondrial
respiratory chain and is composed of 45 subunits in humans, making it one of the largest …

Mitochondria are ubiquitous intracellular organelles found in almost all eukaryotes and
involved in various aspects of cellular life, with a primary role in energy production. The …

The assembly of the five oxidative phosphorylation system (OXPHOS) complexes in the
inner mitochondrial membrane is an intricate process. The human enzymes comprise core …

Activation of the pseudokinase mixed lineage kinase domain-like (MLKL) upon its
phosphorylation by the protein kinase RIPK3 triggers necroptosis, a form of programmed cell …

Mitochondria form intricate networks through fission and fusion events. Here, we identify
mitochondrial dynamics proteins of 49 and 51 kDa (MiD49 and MiD51, respectively) …

Complex I (NADH: ubiquinone oxidoreductase) is the largest multimeric enzyme complex of
the mitochondrial respiratory chain, which is responsible for electron transport and the …

Drp1 (dynamin-related protein 1) is recruited to both mitochondrial and peroxisomal
membranes to execute fission. Fis1 and Mff are Drp1 receptor/effector proteins of …

Mitochondrial complex I is the primary entry point for electrons into the electron transport
chain, required for the bulk of cellular ATP production via oxidative phosphorylation …