Currently, the development of anticancer drug resistance is significantly restricted the clinical
efficacy of the most commonly prescribed anticancer drug. Malignant disease is widely …

Aminothiazole nuclei and their various derivatives have been long used as precursors for
the synthesis of biologically active molecules. As a typical heterocyclic amine, 2 …

In our endeavor towards the development of effective VEGFR-2 inhibitors, three novel series
of phthalazine derivatives based on 1-piperazinyl-4-arylphthalazine scaffold were …

In an attempt to discover new potent inhibitors for Mycobacterium tuberculosis (Mtb), a series
of 2-(2-hydrazinyl) thiazole derivatives with a wide range of substitutions at 2-, 4-and 5 …

In the current work, new thiazolyl–pyrazoline derivatives (1–22) were synthesized and
evaluated for their antifungal effects against pathogenic yeasts and molds using a broth …

Abstract A series of novel 2, 4, 5-trisubstituted 1, 3-thiazole derivatives containing hydrazide–
hydrazine, and carboxamide moiety including 46 compounds T were synthesized, and …

Abstract Twenty-two 1, 3, 4-trisubstituted pyrazole (3a–d),(4a–d),(5a–d),(6a–l) derivatives
were synthesized and structure of newly synthesized compounds were characterized by IR …

In this study, a new series of quinazoline derivatives (3–26) was synthesized and
characterized via physicochemical and spectral means. Treatment of 2-amino-5 …

Inflammation is a complex set of interactions that can occur in tissues as the body's
defensive response to infections, trauma, allergens, or toxic compounds. Therefore, in …

A novel series of 2-acetamido-or 2-propanamido-4-(4-substituted phenyl)-1, 3-thiazoles (11–
34) was designed and synthesized. Compounds were subjected to National Cancer Institute …