Caenorhabditis elegans has emerged as a major model in biomedical and environmental
toxicology. Numerous papers on toxicology and pharmacology in C. elegans have been …

Abstract JASPAR (https://jaspar. elixir. no/) is a widely-used open-access database
presenting manually curated high-quality and non-redundant DNA-binding profiles for …

Single-cell genomics has the potential to revolutionize the study of plant development and
tissue-specific responses to environmental stimuli by revealing heretofore unknown players …

We have produced gene expression profiles of all 302 neurons of the C. elegans nervous
system that match the single-cell resolution of its anatomy and wiring diagram. Our results …

It is not known at present whether neuronal cell-type diversity—defined by cell-type-specific
anatomical, biophysical, functional and molecular signatures—can be reduced to relatively …

The biology and behavior of adults differ substantially from those of developing animals, and
cell-specific information is critical for deciphering the biology of multicellular animals. Thus …

Vitamin B12 is an essential micronutrient that functions in two metabolic pathways: the
canonical propionate breakdown pathway and the methionine/S-adenosylmethionine …

Cytokines are cell-to-cell signaling proteins that play a central role in immune development,
pathogen responses, and diseases. Cytokines are highly regulated at the transcriptional …

Biological systems must possess mechanisms that prevent inappropriate responses to
spurious environmental inputs. Caenorhabditis elegans has two breakdown pathways for …

We collected 60 age-dependent transcriptomes for C. elegans strains including four
exceptionally long-lived mutants (mean adult lifespan extended 2.2-to 9.4-fold) and three …