Recovery from disorders of consciousness: mechanisms, prognosis and emerging therapies

BL Edlow, J Claassen, ND Schiff… - Nature Reviews Neurology, 2021 - nature.com
Substantial progress has been made over the past two decades in detecting, predicting and
promoting recovery of consciousness in patients with disorders of consciousness (DoC) …

The role of the posterior cingulate cortex in cognition and disease

R Leech, DJ Sharp - Brain, 2014 - academic.oup.com
The posterior cingulate cortex is a highly connected and metabolically active brain region.
Recent studies suggest it has an important cognitive role, although there is no consensus …

Network dysfunction after traumatic brain injury

DJ Sharp, G Scott, R Leech - Nature Reviews Neurology, 2014 - nature.com
Diffuse axonal injury after traumatic brain injury (TBI) produces neurological impairment by
disconnecting brain networks. This structural damage can be mapped using diffusion MRI …

Neuropsychology of traumatic brain injury: An expert overview

P Azouvi, A Arnould, E Dromer, C Vallat-Azouvi - Revue neurologique, 2017 - Elsevier
Traumatic brain injury (TBI) is a serious healthcare problem, and this report is a selective
review of recent findings on the epidemiology, pathophysiology and neuropsychological …

Injured brains and adaptive networks: the benefits and costs of hyperconnectivity

FG Hillary, JH Grafman - Trends in cognitive sciences, 2017 - cell.com
A common finding in human functional brain-imaging studies is that damage to neural
systems paradoxically results in enhanced functional connectivity between network regions …

Traumatic brain injury as a disorder of brain connectivity

JP Hayes, ED Bigler, M Verfaellie - Journal of the International …, 2016 - cambridge.org
Objectives: Recent advances in neuroimaging methodologies sensitive to axonal injury
have made it possible to assess in vivo the extent of traumatic brain injury (TBI)-related …

Default-mode network disruption in mild traumatic brain injury

Y Zhou, MP Milham, YW Lui, L Miles, J Reaume… - Radiology, 2012 - pubs.rsna.org
Purpose To investigate the integrity of the default-mode network (DMN) by using
independent component analysis (ICA) methods in patients shortly after mild traumatic brain …

Hyperconnectivity is a fundamental response to neurological disruption.

FG Hillary, CA Roman, U Venkatesan… - …, 2015 - psycnet.apa.org
Objective: In the cognitive and clinical neurosciences, the past decade has been marked by
dramatic growth in a literature examining brain “connectivity” using noninvasive methods …

Imaging assessment of traumatic brain injury

S Currie, N Saleem, JA Straiton… - Postgraduate …, 2016 - academic.oup.com
Traumatic brain injury (TBI) constitutes injury that occurs to the brain as a result of trauma. It
should be appreciated as a heterogeneous, dynamic pathophysiological process that starts …

Multiple resting state network functional connectivity abnormalities in mild traumatic brain injury

MC Stevens, D Lovejoy, J Kim, H Oakes… - Brain imaging and …, 2012 - Springer
Several reports show that traumatic brain injury (TBI) results in abnormalities in the
coordinated activation among brain regions. Because most previous studies examined …