Nanocarriers for skin applications: where do we stand?

N Tiwari, ER Osorio‐Blanco, A Sonzogni… - Angewandte Chemie …, 2022 - Wiley Online Library
Skin penetration of active molecules for treatment of diverse diseases is a major field of
research owing to the advantages associated with the skin like easy accessibility, reduced …

Crossing biological barriers with nanogels to improve drug delivery performance

JC Cuggino, ERO Blanco, LM Gugliotta… - Journal of Controlled …, 2019 - Elsevier
The current limitations in the use of nanocarriers to treat constantly evolving diseases call for
the design of novel and smarter drug delivery systems (DDS). Nanogels (NGs) are three …

Polyglycerols as multi-functional platforms: synthesis and biomedical applications

P Pouyan, M Cherri, R Haag - Polymers, 2022 - mdpi.com
The remarkable and unique characteristics of polyglycerols (PG) have made them an
attractive candidate for many applications in the biomedical and pharmaceutical fields. The …

Polyethers based on short-chain alkyl glycidyl ethers: thermoresponsive and highly biocompatible materials

R Matthes, H Frey - Biomacromolecules, 2022 - ACS Publications
The polymerization of short-chain alkyl glycidyl ethers (SCAGEs) enables the synthesis of
biocompatible polyethers with finely tunable hydrophilicity. Aliphatic polyethers, most …

Thermoresponsive nanogels based on different polymeric moieties for biomedical applications

S Ghaeini-Hesaroeiye, H Razmi Bagtash, S Boddohi… - Gels, 2020 - mdpi.com
Nanogels, or nanostructured hydrogels, are one of the most interesting materials in
biomedical engineering. Nanogels are widely used in medical applications, such as in …

[HTML][HTML] Breaking the barrier-potent anti-inflammatory activity following efficient topical delivery of etanercept using thermoresponsive nanogels

M Giulbudagian, G Yealland, S Hönzke, A Edlich… - Theranostics, 2018 - ncbi.nlm.nih.gov
Topical administration permits targeted, sustained delivery of therapeutics to human skin.
Delivery to the skin, however, is typically limited to lipophilic molecules with molecular …

Enhanced topical delivery of dexamethasone by β-cyclodextrin decorated thermoresponsive nanogels

M Giulbudagian, S Hönzke, J Bergueiro, D Işık… - Nanoscale, 2018 - pubs.rsc.org
Highly hydrophilic, responsive nanogels are attractive as potential systems for the topical
delivery of bioactives encapsulated in their three-dimensional polymeric scaffold. Yet, these …

[HTML][HTML] Replacing PEG-surfactants in self-emulsifying drug delivery systems: Surfactants with polyhydroxy head groups for advanced cytosolic drug delivery

JD Friedl, AM Jörgensen, NMN Le, C Steinbring… - International Journal of …, 2022 - Elsevier
Aim Evaluation of different polyhydroxy surfaces in SEDDS to overcome the limitations
associated with conventional polyethylene glycol (PEG)-based SEDDS surfaces for …

Controlled release of therapeutics from thermoresponsive nanogels: A thermal magnetic resonance feasibility study

Y Ji, L Winter, L Navarro, MC Ku, JS Periquito, M Pham… - Cancers, 2020 - mdpi.com
Thermal magnetic resonance (ThermalMR) accommodates radio frequency (RF)-induced
temperature modulation, thermometry, anatomic and functional imaging, and (nano) …

[HTML][HTML] Nanogels: smart tools to enlarge the therapeutic window of gene therapy

B Espuche, SE Moya, M Calderón - International Journal of Pharmaceutics, 2024 - Elsevier
Gene therapy can potentially treat a great number of diseases, from cancer to rare genetic
disorders. Very recently, the development and emergency approval of nucleic acid-based …